Results 131 to 140 of about 512,213 (312)
Structural biology of ferritin nanocages
FEBS Letters, EarlyView.Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
Using Social Simulation to Explore the Dynamics at Stake in Participatory Research [PDF]
This position paper contributes to the debate on perspectives for simulating the social processes of science through the specific angle of participatory research.
Christophe Le Page, Olivier Barreteau
core
FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
INTREPID Futures Initiative: The future of Academia and trans-disciplinary knowledge production in the urban field, 6th INTREPID Report [PDF]
, 2018 The idea of hosting the 5th INTREPID Action Workshop in Gagliato, Calabria (Italy), between the 20th - 27th July 2017, raised during the London Workshop with the deliberate intention to embed one of the INTREPID research explorations within ongoing ...
Bina, O. +5 more
core
FEBS Letters, EarlyView.Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
Evaluating Participatory Modeling: Developing a Framework for Cross-case Analysis [PDF]
Participatory modeling is increasingly recognised as an effective way to assist collective decision-making processes in the domain of natural resource management. This paper introduces a framework for evaluating projects that have adopted a participatory
Anne Dray +7 more
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New Models of Technology Assessment for Development [PDF]
, 2011 This report explores the role that ‘new models’ of technology assessment can play in improving the lives of poor and vulnerable populations in the developing world. The ‘new models’ addressed here combine citizen and decision-maker participation with
Ely, Adrian +2 more
core +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Citizen Science: which kind of public participation is epistemologically feasible?
Science & PhilosophyProjects concerning the participation of citizens to the scientific research have become very popular in recent years. However, the literature seems not offer much foundational investigations into the epistemological conditions that make citizens ...
Raffaele Mascella, Davide Fazio
doaj +1 more source
Engaging Participatory Literacy through Science Zines
The American Biology Teacher, 2010 Fostering science literacy by engaging students as active participants and communicators of scientific ideas can enhance learning as well as a sense of personal investment. Science “zine” projects can be an effective way to structure this kind of participatory science literacy and flexibly build on specific course content as well as skills in the ...
openaire +1 more source