Results 141 to 150 of about 74,562 (313)
Collaborative fisheries research programs engage stakeholders in data collection efforts, often with the benefit of increasing transparency about the status and management of natural resources. These programs are particularly important in marine systems,
Erin M. Johnston +28 more
doaj +1 more source
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner +14 more
wiley +1 more source
Exploring the challenges of facilitating participatory action research with people living with HIV
Includes bibliographical references.This study describes a Participatory Action Research (PAR) project that was conducted in Masiphumelele (an informal settlement near Cape Town) in 2003/2004 with a group of 5 black, HIV positive people. The original aim
Butchart, Wendy Ann
core
Federal monies to remediate lead in drinking water support utilities companies to upgrade infrastructure. There is little upgrade support for private property owners on public or private sources of water, and sparse data available on the remaining ...
Danielle E Lin Hunter +3 more
doaj +1 more source
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak +10 more
wiley +1 more source
Participatory Science Newsletter 2025_05_20 [PDF]
In this edition of the UNH Participatory Sciences Newsletter, we offer news and resources on The Power of Participatory Sciences. These include a story about UNH graduate student Lauren White\u27s work using participatory science data about horseshoe ...
Eberhardt, Alyson L. +2 more
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Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena +15 more
wiley +1 more source
Participatory technology development has been used for quite some time. However, little is known about how farmers perceive participatory methods and processes.
Twomlow, Steve +2 more
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