Results 151 to 160 of about 74,562 (313)
Participatory soil citizen science
Citizen science is a participatory research method that actively involves and engages the public in scientific enquiry to generate new knowledge or understanding.
Miloczki, Julia +9 more
core +1 more source
Molecular Oncology, EarlyView.Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen +9 more
wiley +1 more source
Identifying the appropriate germplasm to be improved is a key component of any participatory breeding effort because of its implications for impacts on social welfare and genetic diversity. This paper describes a method developed to select a subset of 17
Aragon, Flavio +6 more
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Redressing Ecological Poverty Through Participatory Democracy: Case Studies from India [PDF]
or the rural poor – who depend above all the land for their survival – a central development challenge is to sustain a base of natural capital that can support a robust local economy.
Anil Agarwal, Sunita Narain
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A conception of computing technology better suited to distributed participatory design [PDF]
, 2006 Distributed participatory design aspires to standards of inclusivity and humanity in introducing technology to the workplace that are hard to attain. The demands it makes upon the development and use of computing technology are particularly topical, as ...
Meurig Beynon +3 more
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Building an inclusive botany: The “radicle” dream
Plants, People, PlanetSocietal Impact Statement It is important to recognize how our current understanding of plants has been shaped by diverse cultural contexts, as this underscores the importance of valuing and incorporating contributions from all knowledge systems in ...
Makenzie E. Mabry +9 more
doaj +1 more source
Molecular Oncology, EarlyView.Circulating tumor cells (CTCs) and plasma cell‐free DNA (cfDNA) were analyzed to detect ESR1 mutations and methylation in patients with advanced breast cancer. CTC‐derived DNA showed higher sensitivity for mutation detection and revealed complementary genetic and epigenetic alterations, highlighting the added value of CTC analysis for understanding ...
Dimitra Stergiopoulou +12 more
wiley +1 more source
Interpreting the effects of DNA polymerase variants at the structural level
Molecular Oncology, EarlyView.Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi +7 more
wiley +1 more source
Reflections on Participatory Science for TELSci2.0
, 2009 Technology is undoubtedly enabling scientists to do research in interesting new ways. However, Science 2.0 is about more than improved workflows, efficiency and sharing within communities, it also offers opportunities to greatly broaden participation ...
Underwood, J +7 more
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Molecular Oncology, EarlyView.Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen +14 more
wiley +1 more source