Results 51 to 60 of about 1,467,838 (296)
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
On the micro mechanics of one-dimensional normal compression [PDF]
, 2015 Discrete-element modelling has been used to investigate the micro mechanics of one-dimensional compression. One-dimensional compression is modelled in three dimensions using an oedometer and a large number of particles, and without the use of ...
Ashby M. F. +6 more
core +2 more sources
FEBS Letters, EarlyView.This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel +13 more
wiley +1 more source
FEBS Letters, EarlyView.Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source
Particle-size characteristics of the vertical dust profiles of two contrasting dust events in the Channel Country of western Queensland, Australia [PDF]
, 2006 Spatial and temporal variations in vegetation and soil surface conditions of rangelands add a level of complexity to wind erosion processes which is often difficult to model or measure.
Butler, Harry J. +2 more
core
Using ultra-short pulses to determine particle size and density distributions [PDF]
, 2007 We analyze the time dependent response of strongly scattering media (SSM) to ultra-short pulses of light. A random walk technique is used to model the optical scattering of ultra-short pulses of light propagating through media with random shapes and ...
Boller, Klaus. -J. +2 more
core +3 more sources
AAA+ protein unfoldases—the Moirai of the proteome
FEBS Letters, EarlyView.AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley +1 more source
Measurements of the backscattering characteristics of suspensions having a broad particle size distribution [PDF]
, 2007 Acoustic backscatter systems (ABS) can be used to non-intrusively measure profiles of both the concentration and particle size of suspended sediments in the marine environment.
Moate, Benjamin D., Thorne, Peter D.
core
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
Comparison of Particle Size Distribution Models for Polymer Swelling
Hungarian Journal of Industry and Chemistry, 2018 In polymer technologies, various particle shapes and size distributions can be found. One of these are heterodisperse polymer beads. The capabilities of polymer swelling can be used in industries, e.g in the production of ion-exchange resins, to ...
Wirnhardt Ádám, Varga Tamás
doaj +1 more source