Results 61 to 70 of about 1,467,838 (296)

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

SUCELL Test Conditions Optimization of HELOS/BF Laser Particle Size Analyzer

Yankuang ceshi, 2013
The Laser Particle Size Analyzer is being more widely used due to its fast test speed, convenient operation and good repeatability, to name a few of its qualities.
LU Xin-cheng, CAO Jing-yang
doaj  

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

PARTICLE SIZE DISTRIBUTION APPLIED TO MILK POWDER REHYDRATION

Química Nova
Besides increasing shelf life of fluid milk, milk powder has physical and functional properties that allow it to be used as ingredient. The rehydration process is complex and happens in four steps: wettability, sinkability, dispersibility and solubility.
Júlia d’Almeida Francisquini, Evandro Martins, Isis Rodrigues Toledo Renhe, Luiz Fernando Cappa de Oliveira, Rodrigo Stephani, Ítalo Tuler Perrone, Antônio Fernandes de Carvalho   +6 more
doaj   +1 more source

Universality of temperature distribution in granular gas mixtures with a steep particle size distribution

, 2014
Distribution of granular temperatures in granular gas mixtures is investigated analytically and numerically. We analyze space uniform systems in a homogeneous cooling state (HCS) and under a uniform heating with a mass-dependent heating rate $\Gamma_k ...
Bodrova, Anna, Brilliantov, Nikolay, Levchenko, Denis   +2 more
core   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

On the Particle Size Distribution of a Basaltic Till

Soils and Foundations, 2011
Stress and strain history play a major role in defining the final grading of a soil, and by studying how the particle size distribution of a soil evolves with stress and strain it may be possible to highlight some important aspects of the sediment past history.
Altuhafi, F, Sammonds, P, Baudet, BA
openaire   +4 more sources

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

Evaluation of particle size distribution of granular blasting materials based on the fractal theory

Advances in Mechanical Engineering, 2019
The particle size distribution of granular blasting materials has a vital influence on the filling quality of earth-rockfill dams. The engineering experience-based method used to evaluate the particle size distribution has shortcomings at both the ...
Jiejie Ji, Qiang Yao, Faming Wu, Hongtao Li   +3 more
doaj   +1 more source

A unified analysis of nano-to-microscale particle dispersion in tubular blood flow

, 2019
Transport of solid particles in blood flow exhibits qualitative differences in the transport mechanism when the particle varies from nanoscale to microscale size comparable to the red blood cell (RBC).
Aidun, Cyrus K., Clausen, Jonathan R., Liu, Zixiang, Rao, Rekha R.   +3 more
core   +1 more source