Results 71 to 80 of about 9,096,569 (249)
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Molecular Oncology, EarlyView.Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq +8 more
wiley +1 more source
Molecular Oncology, EarlyView.Extracellular vesicle (EV) lipidomic profiling of plasma and ascites from patients with high‐grade serous ovarian cancer and of ovarian cancer cell lines reveals enrichment of triglycerides (TGs), diacylglycerols (DGs), phosphatidylcholine (PCs), sphingomyelins (SMs), reflecting tumor metabolic reprogramming.
Shikha Rani +9 more
wiley +1 more source
Method for Particle Size Control During the Drying and Granulation in Fluidized Bed [PDF]
, 2001 The fluidized bed process presented in this paper is suitable for recovery of solids from solutions in the form of granules. The solution is sprayed into the bed and as solvent evaporates, solid material is deposited on the surface of fluidizing ...
Gyenis, János, Dencs, B., Tardos, I. G.
core +1 more source
Study on Particle Size of Coal Sample Measured by Dynamic Image Method
Meikuang Anquan, 2020 Coal samples from Hexing Coal Mine in Yunnan Province were selected and 8 samples from 1 mm to 3 mm were measured by dynamic image method, each of which was 20 g.
LONG Qingming
doaj +1 more source
Molecular Oncology, EarlyView.In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico +5 more
wiley +1 more source
The relationship between gunshot-residue particle size and Boltzmann distribution
Forensic Sciences Research, 2020 Gunshot-residue (GSR) particles usually form spherical structures, have special dimensions, and a composition that consists of burned and partially unburned matter with a 0.5–50-µm diameter (sometimes larger).
İlker Kara
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Molecular Oncology, EarlyView.Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez +5 more
wiley +1 more source
Particle Size Control by Torque Measurements in Fluidized Beds during Drying and Granulation from Solutions [PDF]
, 2001 The fluidized bed process presented in this paper is suitable to recover solids from solution in form of granules. Solution is sprayed into the bed and, as the solvent evaporates, solid material is deposited on the surface of fluidizing particles ...
Gyenis, János, Dencs, B., Tardos, I. G.
core +1 more source
Evaluation of particle size distribution of granular blasting materials based on the fractal theory
Advances in Mechanical Engineering, 2019 The particle size distribution of granular blasting materials has a vital influence on the filling quality of earth-rockfill dams. The engineering experience-based method used to evaluate the particle size distribution has shortcomings at both the ...
Jiejie Ji +3 more
doaj +1 more source