Results 51 to 60 of about 67,146 (302)

AKR breakup and auroral particle acceleration at substorm onset [PDF]

open access: yes, 2008
The dynamical behavior of auroral kilometric radiation (AKR) is investigated in connection with auroral particle acceleration at substorm onsets using high-time-resolution wave spectrograms provided by Polar/PWI electric field observations.
Morioka, A.   +10 more
core  

The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome

open access: yesFEBS Letters, EarlyView.
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley   +1 more source

A new type of accelerator for charged particle cancer therapy [PDF]

open access: yes, 2013
Non-scaling Fixed Field Alternating Gradient accelerators (ns-FFAGs) show great potential for the acceleration of protons and light ions for the treatment of certain cancers.
Rob Edgecock   +3 more
core   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

open access: yesFEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee   +7 more
wiley   +1 more source

Pattern Recognition, Tracking and Vertex Reconstruction in Particle Detectors [PDF]

open access: yes, 2021
This open access book is a comprehensive review of the methods and algorithms that are used in the reconstruction of events recorded by past, running and planned experiments at particle accelerators such as the LHC, SuperKEKB and FAIR.
Strandlie, Are, Frühwirth, Rudolf
core   +2 more sources

Observation of 99Mo radioactivity produced in natural molybdenum irradiated with an electron beam from a linear industrial accelerator

open access: yesNukleonika
The authors present the first observation of the production of 99Mo using a direct electron beam obtained from an electron linear accelerator in the 10–20 MeV energy region.
Zawistowski Tobiasz   +7 more
doaj   +1 more source

Active Galactic Nuclei as Potential Sources of Ultra-High Energy Cosmic Rays

open access: yesUniverse, 2022
Active Galactic Nuclei (AGNs) and their relativistic jets belong to the most promising class of ultra-high-energy cosmic ray (UHECR) accelerators. This compact review summarises basic experimental findings by recent instruments, and discusses possible ...
Frank M. Rieger
doaj   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

Topics in Energy Release and Particle Acceleration in the Heliosphere [PDF]

open access: yes, 2014
This thesis investigates both the release of energy in solar flares, and the acceleration and transport of particles in various astrophysical situations.
Armstrong, Craig Keith
core  

Understanding the Physics of Particle Accelerators [PDF]

open access: yes
This open access book introduces readers to the physics of particle accelerators, by means of beam dynamics simulations and exercises using the computer code ZGOUBI.
Méot, François
core   +1 more source

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