Results 51 to 60 of about 345,959 (285)
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
AstronomyHigh-energy particles may be accelerated widely in stellar coronae; probably by the same processes we find in the Sun. Here, we have learned of two physical mechanisms that dominate the acceleration of solar energetic particles (SEPs).
Donald V. Reames
doaj +1 more source
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
A Model for Nonthermal Particle Acceleration in Relativistic Magnetic Reconnection
The Astrophysical Journal Letters, 2023 The past decade has seen an outstanding development of nonthermal particle acceleration in magnetic reconnection in magnetically dominated systems, with clear signatures of power-law energy distributions as a common outcome of first-principles kinetic ...
Xiaocan Li, Fan Guo, Yi-Hsin Liu, Hui Li
doaj +1 more source
Orbital evolution under the action of fast interstellar gas flow with non-constant drag coefficient
, 2012 The acceleration of a spherical dust particle caused by an interstellar gas flow depends on the drag coefficient which is, for the given particle and flow of interstellar gas, a specific function of the relative speed of the dust particle with respect to
Alouani-Bibi +25 more
core +1 more source
Nonlinear interaction of charged particles with strong laser pulses in a magnetic undulator
Physical Review Special Topics. Accelerators and Beams, 2010 Laser acceleration due to the nonlinear-threshold phenomena of charged particle “reflection” and capture by slowed wave in a magnetic undulator is considered. The obtained numerical results prove the particle reflection and capture phenomena in the field
H. K. Avetissian, Kh. V. Sedrakian
doaj +1 more source
Nonlinear Particle Acceleration in Relativistic Shocks [PDF]
, 2002 Monte Carlo techniques are used to model nonlinear particle acceleration in parallel collisionless shocks of various speeds, including mildly relativistic ones.
Achterberg +34 more
core +2 more sources
Molecular Oncology, EarlyView.Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova +14 more
wiley +1 more source
Particle acceleration in subcycle optical cells
Physical Review Special Topics. Accelerators and Beams, 2014 A single laser pulse with spot size smaller than half its wavelength (w_{0}
F. Terranova
doaj +1 more source
Particles in Relativistic MHD Jets. I. Role of Jet Dynamics in Particle Acceleration
The Astrophysical Journal, 2023 Relativistic jets from (supermassive) black holes are typically observed in nonthermal emission, caused by highly relativistic electrons. Here, we study the interrelation between three-dimensional (special) relativistic magnetohydrodynamics, and particle
Ravi Pratap Dubey +2 more
doaj +1 more source