Results 41 to 50 of about 167,926 (291)

Multi-Agent Cooperation for Particle Accelerator Control [PDF]

open access: yes, 1996
We present practical investigations in a real industrial controls environment for justifying theoretical DAI (Distributed Artificial Intelligence) results, and we discuss theoretical aspects of practical investigations for accelerator control and ...
Skarek, P., Varga, László Zsolt
core   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Particle Accelerators [PDF]

open access: yes, 1955
In the most general sense, an accelerator is any device designed to give kinetic energy to ions or electrons. According to this definition the earliest cathode ray and canal ray tubes, made before the turn of the century were accelerators, the same principle is used in the x-ray tube, the cathode ray oscilloscope, the mass spectrograph, the electron ...
openaire   +4 more sources

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Strip-based Scintillation Detector for Dual-readout High-granularity Calorimetry [PDF]

open access: yesEPJ Web of Conferences
New calorimeter technology is being developed for future collider experiments. We are developing a calorimeter that integrates two technologies, a high-granularity calorimeter and a dual-readout calorimeter, and has high time resolution at a picosecond ...
Ogawa Hiroyasu   +9 more
doaj   +1 more source

Beam Cleaning and Collimation Systems [PDF]

open access: yes, 2016
Collimation systems in particle accelerators are designed to dispose of unavoidable losses safely and efficiently during beam operation. Different roles are required for different types of accelerator.
Redaelli, S.
core   +3 more sources

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

open access: yesMolecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung   +17 more
wiley   +1 more source

Accelerator modes of square well system

open access: yes, 2005
We study accelerator modes of a particle, confined in an one-dimensional infinite square well potential, subjected to a time-periodic pulsed field. Dynamics of such a particle can be described by one generalization of the kicked rotor. In comparison with
Benkadda   +20 more
core   +1 more source

Efficient control of accelerator maps [PDF]

open access: yes, 2011
Recently, the Hamiltonian Control Theory was used in [Boreux et al.] to increase the dynamic aperture of a ring particle accelerator having a localized thin sextupole magnet. In this letter, these results are extended by proving that a simplified version
Boreux, Jehan   +4 more
core   +4 more sources

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

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