Results 1 to 10 of about 61,960 (301)

Study on the Optimized Muffler with Function of PM Filtration for Non-Road Diesel Engines

open access: yesAtmosphere, 2022
With a high thermal efficiency, high reliability and good fuel economy, diesel engines have been widely used. However, with the increasingly stringent standards regarding non-road diesel engine emissions, diesel engines can hardly satisfy the particle ...
Long Feng   +7 more
doaj   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

open access: yesFEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace   +6 more
wiley   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

open access: yesFEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee   +7 more
wiley   +1 more source

Track-Before-Detect Algorithm Based on Improved Auxiliary Particle PHD Filter under Clutter Background

open access: yesLeida xuebao, 2019
Under the clutter background condition, the existing particle filter pre-detection tracking algorithm based on Probability Hypothesis Density (PHD) filtering is not accurate enough to estimate the number of targets in dense multi-objectives.
PEI Jiazheng   +4 more
doaj   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

Applying sequential Monte Carlo methods into a distributed hydrologic model: lagged particle filtering approach with regularization [PDF]

open access: yesHydrology and Earth System Sciences, 2011
Data assimilation techniques have received growing attention due to their capability to improve prediction. Among various data assimilation techniques, sequential Monte Carlo (SMC) methods, known as "particle filters", are a Bayesian learning process ...
S. J. Noh   +3 more
doaj   +1 more source

An Adaptive Particle Filter for Target Tracking Based on Double Space-Resampling

open access: yesIEEE Access, 2021
Particle filter has been widely applied in nonlinear target tracking due to the ability to carry multiple hypothesis and relaxation of linearity/Gaussian assumption.
Zheng Gong, Gang Gao, Mingang Wang
doaj   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

Log-PF: Particle Filtering in Logarithm Domain

open access: yesJournal of Electrical and Computer Engineering, 2018
This paper presents a particle filter, called Log-PF, based on particle weights represented on a logarithmic scale. In practical systems, particle weights may approach numbers close to zero which can cause numerical problems.
Christian Gentner   +2 more
doaj   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

open access: yesMolecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova   +14 more
wiley   +1 more source

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