Myogenic Fusogen‐Engineered Lipid Nanoparticles Enhance mRNA Delivery in Skeletal Muscle
This study reports a biomimetic strategy of engineering full‐length Myomaker, a muscle‐specific fusogen, into lipid nanoparticles (LNPs) to harness the native myoblast fusion capability for skeletal muscle mRNA delivery. The resulting Mymk‐LNPs enhance transfection in differentiating myocytes and enable Cre‐mediated reporter activation in injured ...
Fangyu Zhang +18 more
wiley +1 more source
Application of particle filter algorithm based on chaotic sequences and improved t-distribution in UWB indoor positioning. [PDF]
Li B +5 more
europepmc +1 more source
An integrated pulmonary mRNA delivery platform combining novel biodegradable syringic acid‐derived ionizable lipids, design‐of‐experiments formulation optimization, and vibrating‐mesh nebulizer engineering enabled stable aerosolization and efficient lung delivery.
Neha Kaushal +21 more
wiley +1 more source
Keratin recovered from animal‐hair textile waste is fractionated and blended with cellulose to produce continuously spun hybrid fibers. Selecting the high‐molecular‐weight keratin fraction enables 30 wt.% keratin incorporation while maintaining high strength in dry and wet states.
Mian Zhai +6 more
wiley +1 more source
Temperature-dependent thermoelectric behavior of metal-doped nanoporous carbon with tailored pore structures for multilevel temperature sensing. [PDF]
Park M +4 more
europepmc +1 more source
Schematic illustration of LNP‐MPG nuclei‐targeting delivery of HMW‐FGF2 promoting histone acetylation to regulate the fate of DPSCs and treat spinal cord injury. LNPs components include pHMW‐FGF2 plasmid, DSPC, Dlin‐MC3‐DMA, cholesterol, and PEG2000, and are modified with MPG to form HMW‐FGF2@LNP‐MPG (HLM). HLM nuclei‐targets DPSCs to deliver HMW‐FGF2,
Heng Zhou +6 more
wiley +1 more source
Cooperative Tracking of Vessel Trajectory by Multi-Static Passive Stations Using an MC-RMPF. [PDF]
Liu B, Kong L, Wu P.
europepmc +1 more source
Photo‐Switchable Molecular Module Programming PET Biodegradation in Aquatic Environments
We address the plastic durability paradox by integrating an itaconic acid–derived pyrrolidone module into polymer backbones. Sunlight in water triggers Norrish Type I ring‐opening and hydrophilization, enabling rapid biodegradation into nontoxic minerals.
Mohammad Asif Ali +16 more
wiley +1 more source
Inferring the causes of noise from binary outcomes: A normative theory of learning under uncertainty. [PDF]
Fang X, Piray P.
europepmc +1 more source
Data-Driven Fusion Algorithms for Temperature-Drift Compensation of MEMS Gyroscopes: A Mini Review. [PDF]
Lan H, Xu Y.
europepmc +1 more source

