Results 91 to 100 of about 6,416,888 (307)

The Effect of Barrel Configurations on the Porosity During HVAF Thermal Spray Ni-Based Amorphous Coatings: Numerical Simulation and Experiment [PDF]

Archives of Metallurgy and Materials
The relationship between barrel configurations and porosity of a Ni-based amorphous coating (AM) that is fabricated using a high-velocity air fuel (HVAF) process was revealed by both numerical and experimental methods.
Nianchu Wu, Tingting Li, Xiaotian Su
doaj   +1 more source

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

FEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young, Omar Arias‐Gaguancela, Fiona Gibson, Morgan Grainger, Jodie Score, Amit Nathubhai, Mauricio Cafiero, Lee Richard Machado   +7 more
wiley   +1 more source

Experimental Study of the Effective Vortex Length in Small-Diameter Cyclones

Aerosol and Air Quality Research
This study experimentally investigated the effective vortex length (Lev) in cyclone separators to resolve discrepancies between theoretical predictions and actual performance. Unlike previous studies that focused on the natural vortex length (Ln) derived
Maxie Lin, Yu-Mei Kuo, Jason Lin, Hsiao-Yi Hung, Chih-Wei Lin, Cindy Lin, Sheng-Hsiu Huang, Chih-Chieh Chen   +7 more
doaj   +1 more source

Single-particle analysis of full-length human poly(ADP-ribose) polymerase 1

Biophysics and Physicobiology, 2019
PolyADP-ribosylation (PARylation) is a posttranslational modification that is involved in the various cellular functions including DNA repair, genomic stability, and transcriptional regulation.
Kenichi Kouyama, Kouta Mayanagi, Setsu Nakae, Yoshisuke Nishi, Masanao Miwa, Tsuyoshi Shirai   +5 more
doaj   +1 more source

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

FEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero, Maria Kopsida, Nathalie Arendt, Hans Lennernäs, Markus Sjöblom, Femke Heindryckx   +5 more
wiley   +1 more source

Variable-dimension swarm meta-heuristic for the optimal placement of relay nodes in wireless sensor networks

International Journal of Distributed Sensor Networks, 2017
A wireless sensor network is a network consisting of wireless sensor nodes. There are usually requirements that need to be met when deploying a wireless sensor network, one being the placement of nodes.
Yi-Han Xu, Wan-Guo Jiao, Yin Wu, Jun Song   +3 more
doaj   +1 more source

Three-particle quantization condition in a finite volume: 1. The role of the three-particle force

Journal of High Energy Physics, 2017
Using non-relativistic effective Lagrangians in the particle-dimer picture, we rederive the expression for the energy shift of a loosely bound three-particle bound state of identical bosons in the unitary limit.
Hans-Werner Hammer, Jin-Yi Pang, Akaki Rusetsky   +2 more
doaj   +1 more source

The crystal structure of the Borrelia burgdorferi nicotinamidase BBE22 resolves a long‐standing annotation error

FEBS Open Bio, EarlyView.
The crystal structure of Borrelia burgdorferi nicotinamidase (PncA/BBE22) reveals the correct full‐length protein initiated from a non‐canonical AUU start codon. The structure validates previous biochemical findings and resolves a long‐standing annotation error, demonstrating that the truncated database sequence is structurally incompatible with the ...
Kalvis Brangulis
wiley   +1 more source

Guiding AlphaFold to predict how Munc13‐1 opens Syntaxin‐1

FEBS Open Bio, EarlyView.
The syntaxin‐1 Habc‐domain (orange), linker (pink) and SNARE motif (yellow) form a closed conformation that binds to Munc18‐1 (violet) and is opened by the Munc13‐1 MUN domain (cyan) to form the SNARE complex that triggers neurotransmitter release.
Madhurima Chattopadhyay, Junjie Xu, Josep Rizo   +2 more
wiley   +1 more source

Transient Electrophoresis in Suspensions of Charged Porous Particles

Fluids
The start-up of electrophoretic motion in a suspension of uniformly charged, porous, spherical particles within an arbitrary electrolyte solution under a suddenly applied electric field is investigated. The unsteady Stokes/Brinkman equations, modified to
Wei Z. Chen, Huan J. Keh
doaj   +1 more source