Results 31 to 40 of about 4,195,211 (256)

Particle Migration and Clogging in Porous Media: A Convergent Flow Microfluidics Study

Journal of Geophysical Research - Solid Earth, 2019
The migration and retention of fine particles in porous media are important phenomena in natural processes and engineering applications. Migrating particles experience physicochemical interactions with carrier fluids, pore walls, and other migrating ...
Q. Liu, Budi Zhao, J. Santamarina
semanticscholar   +1 more source

Experimental investigation on particle migration behaviour of dredged clays with high initial water contents under vacuum pressure

Yantu gongcheng xuebao
A vacuum consolidation model equipment is designed for performing a series of vacuum consolidation tests on two dredged clays with different liquid limits reconstituted at different initial water contents. The experimental results indicate that the ratio
ZENG Lingling 1, WANG Qizhong 1, LIN Xiaoxin 2
doaj   +1 more source

Visualization experimental study on fracture development and particle migration in hydrate-bearing sediments during hydrate dissociation

Yantu gongcheng xuebao
Fracture development and particle migration in hydrate reservoir induced by hydrate dissociation and gas production commonly occurr during marine hydrate exploitation, significantly affecting gas production efficiency and sand production characteristics.
WANG Lujun 1, 2, HONG Xiaojun 1, 2, SONG Haoqi 1, 2, YANG Haochen 1, 2, YE Zhigang 1, 2, YAN Bingfa 1, 2, ZHU Bin 1, 2
doaj   +1 more source

Structure‐forward targeting of claudins with synthetic binders

FEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Analysis of Gravel Migration Patterns During Vibration Rolling and Their Impact on GCL Performance Based on DEM

Buildings
In this study, a multilayer composite rolling model consisting of a rolling wheel, a protective layer, a GCL, and a support layer was constructed by the discrete element method (DEM).
Hu Huang, Feihao Chen, Qingming Qiu, Ruihang Li, Lixia Guo   +4 more
doaj   +1 more source

Modeling on Effect of Particle Sediment on Fluid Flow and Heat Transfer of Solid–Fluid Suspension

Energies, 2021
A two-way coupling particle flux model is proposed for studying the multi-component solid–fluid suspension. The suspension mixture is treated as a non-linear single-phase fluid and the migration of the solid particles is modeled by a particle flux ...
Yan Wu, Wei-Tao Wu
doaj   +1 more source

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

FEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt, Ana‐Maria Sandru, Georg Vucak, Sebastian Didusch, Biljana Riemelmoser, Karin Ehrenreiter, Markus Hartl, Lukas A. Huber, Manuela Baccarini   +8 more
wiley   +1 more source

Numerical simulation of inertial microfluidics: a review

Engineering Applications of Computational Fluid Mechanics, 2023
Since the proposal of inertial microfluidics in 2007, it has been widely used for particle focusing and separation with superior performances. The particle migration behaviour in microchannel is extremely complicated involving various parameters ...
Ruiju Shi
doaj   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source