Results 51 to 60 of about 4,195,211 (256)

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source

Simulation of seepage erosion process in porous media based on particle-seepage coupling

Yantu gongcheng xuebao
This study investigates the mechanisms of fines migration and deposition in porous media by using a particle-seepage coupling method. A cylindrical porous media model is constructed by PFC3D, and a seepage program is developed in Python to achieve two ...
GAO Wenzhe 1, ZHANG Pengwei 1, 2, ZHANG Hengqi 1
doaj   +1 more source

Research on the Inertial Migration Characteristics of Bi-Disperse Particles in Channel Flow

Applied Sciences, 2021
The inertial focusing effect of particles in microchannels shows application potential in engineering practice. In order to study the mechanism of inertial migration of particles with different scales, the motion and distribution of two particles in ...
Dongmei Chen, Jianzhong Lin, Xiao Hu
doaj   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source

Quantitative Characterization Method of Additional Resistance Based on Suspended Particle Migration and Deposition Model

Energies
The phenomenon of pore blockage caused by injected suspended particles significantly impacts the efficiency of water injection and production capacity release in offshore oilfields, leading to increased additional resistance during the injection process.
Huan Chen, Yanfeng Cao, Jifei Yu, Xiaopeng Zhai, Jianlin Peng, Wei Cheng, Tongchuan Hao, Xiaotong Zhang, Weitao Zhu   +8 more
doaj   +1 more source

Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells

FEBS Open Bio, EarlyView.
Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim, Marco Corazzari, Iman Osman, Jane Armstrong, Noel Carter   +4 more
wiley   +1 more source

Water–rock two-phase flow model for water inrush and instability of fault rocks during mine tunnelling

International Journal of Coal Science & Technology, 2023
Water inrush hazard is one of the major threats in mining tunnel construction. Rock particle migration in the seepage process is the main cause of water inrush pathway and rock instability.
Dan Ma, Hongyu Duan, Qiang Li, Jiangyu Wu, Wen Zhong, Zhen Huang   +5 more
doaj   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Particle migration in bounded shear flow of Giesekus fluids

, 2020
In this paper, the migrations of two interacting particles in a three-dimensional bounded shear flow of Giesekus fluids are numerically investigated using the direct forcing/fictitious domain method for the Weissenberg number ranging from 0.1 to 1.0, the
Bingrui Liu, Jianzhong Lin, X. Ku, Zhaosheng Yu   +3 more
semanticscholar   +1 more source

Malformin A1–mediated cytotoxicity in ovarian cancer cells occurs through pyroptosis and autophagy

FEBS Open Bio, EarlyView.
This study investigated the effects of the natural compound Malformin A1 (MA1) on the cytoskeleton that regulates cell proliferation and migration. Disruption of the cytoskeleton can impair these processes and promote cancer cell death. MA1 disrupted cytoskeletal organization, induced DNA damage, inflammation, activated autophagy, and pyroptosis ...
Nada Abdullah Hassan, Ikram A. Burney, Shika Hanif Malgundkar, Siva Ramamoorthy, Ressin Varghese, Mohamed A. Al‐Kindi, Hamad Al Riyami, Shadia Al Bahlani, Sergey Dobretsov, Syed Imran Hassan, Benjamin K. Tsang, Yahya Tamimi   +11 more
wiley   +1 more source