Results 61 to 70 of about 4,195,211 (256)

Accurate and noninvasive prostate cancer detection using plasma‐derived extracellular vesicle RNA

FEBS Open Bio, EarlyView.
Plasma extracellular vesicles were captured with WGA‐conjugated magnetic beads and profiled for RNA biomarkers. A three‐RNA panel (NM_024955, NR_047469, and NR_002564) distinguished prostate cancer from healthy controls and benign prostatic hyperplasia, supporting a simple, noninvasive approach to improve prostate cancer detection.
Hanping Wei, Haoran Wu, Wei Feng
wiley   +1 more source

Structural studies and functional engineering of NanX: an anhydro‐sialic acid transporter from Escherichia coli

FEBS Open Bio, EarlyView.
Biophysical characterisation shows that NanX, a membrane transport protein from the major facilitator superfamily (MFS), forms both monomers and dimers after purification. AlphaFold modelling and substrate docking provide information on residues likely involved in substrate recognition for NanX and another MFS member, NanT.
Michael C. Newton‐Vesty, Kelsi R. Hall, Zachary D. Tillett, Liam S. Turk, James S. Davies, Michael J. Currie, Hamish G. Brown, Sepideh Valimehr, Peter D. Mace, Andrew E. Whitten, Santosh Panjikar, Eric Hanssen, Rachel A. North, Renwick C.J. Dobson   +13 more
wiley   +1 more source

Pore-scale modelling of particle migration in loose sandstone

Frontiers in Earth Science
During the development of loose sandstone reservoirs, the issue of production decline and bottomhole pressure reduction caused by particle migration is widespread, directly impacting well productivity. Understanding the mechanism of particle migration in
Wei Zheng, Wei Zheng, Chenyang Tang, Chenyang Tang, Shaobin Cai, Shaobin Cai, Yufei He, Yufei He, Junzhe Jiang, Junzhe Jiang, Ke Li, Ke Li, Zhaonian Zhang, Lifeng Chen   +13 more
doaj   +1 more source

GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma

FEBS Open Bio, EarlyView.
GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain, Elise Buret, Le Hoang Thanh Nguyen, Marion Cocheteux, Nicolas Touya, Mélanie Dhayer, Romain Dubois, Frank Lafont, Sebastien Janel, Patrice Maboudou, Steve Lancel, Philippe Marchetti   +11 more
wiley   +1 more source

Effect of Leaching on Particle Migration and Pore Structure of Ionic Rare Earth Ores with Different Fine Particle Contents

Metals
In in situ leaching, fine particles can be stripped and transported with the leach solution, significantly altering the particle size distribution and pore structure of each layer of the rare earth ore body.
Yunzhang Rao, Jiazheng Wan, Shujun Tan, Zhihua Yang, Guozhu Rao, Qiang Huang, Yangjun Xie, Qiande Lai   +7 more
doaj   +1 more source

Effects of Add‐On Icosapent Ethyl With Standard Treatment on Functional Outcomes and Inflammatory Biomarkers in Acute Ischemic Stroke: A Blinded Randomized Controlled Trial

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Ischemic stroke, a major cause of mortality and long‐term disability, results from the abrupt cessation of cerebral blood flow due to vascular occlusion or rupture. Icosapent Ethyl (EPA‐EE), approved for hypertriglyceridemia, has anti‐inflammatory and antithrombotic properties that may lessen ischemic damage.
Mitra Mahmoudi Meymand, Seyed Hossein Aghamiri, Saeed Mohmammad Soleymani, Shadiyeh Bararpoor Poshkohi, Samaneh Masoudi, Hadi Esmaily   +5 more
wiley   +1 more source

Variations of hydraulic properties of granular sandstones during water inrush : effect of small particle migration

, 2017
The evaluation of the hydraulic properties evolution of granular sandstones in relation with groundwater inrush within faults is an important issue for mining engineering applications.
D. Ma, M. Rezania, Hai-Sui Yu, H. Bai
semanticscholar   +1 more source

Microstructural Evolution and Vacancy Defect Formation in Mn–Mo–Ni RPV Steel Under Low Cycle Fatigue: Insights From EBSD and PALS

Advanced Engineering Materials, EarlyView.
Low‐cycle fatigue damage in Mn–Mo–Ni reactor pressure vessel steel is examined using a combined electron backscatter diffraction and positron annihilation lifetime spectroscopy approach. The study correlates texture evolution, dislocation substructure development, and vacancy‐type defect formation across uniform, necked, and fracture regions, providing
Apu Sarkar, Dhanadeep Dutta, G. Bharat Reddy   +2 more
wiley   +1 more source

5G network slicing function migration mechanism based on particle swarm optimization algorithm

网络与信息安全学报, 2018
In multi-application scenarios of 5G,data traffic often increases dramatically.Virtual machine resources in network slicing may not meet the normal needs of users.In view of this,a network slicing function migration mechanism aiming at load balancing was
Qiang CHEN, Caixia LIU, Lingshu LI
doaj   +3 more sources

Effect of oxidizing working fluid on permeability of organic-rich shale

Youqicang pingjia yu kaifa, 2020
Organic-rich shale deposits in the anoxic reductive environment, and is rich in pyrite, chlorite, organic matter and other reductive components. In the process of oil and gas development, a large amount of oxidizing working fluids enter the reservoir ...
YOU Lijun, ZHOU Yang, KANG Yili, DOU Liandong, CHENG Qiuyang   +4 more
doaj