Results 101 to 110 of about 826,123 (296)

Primordial bound systems of superheavy particles as the source of ultra-high energy cosmic rays

, 2003
Annihilation of superheavy particles in primordial bound systems is considered as the source of Ultra High Energy Cosmic Rays (UHECR).Charge conservation makes them to be produced in pairs, and the estimated separation of particle and antiparticle in ...
Alday, Aldazabal, Benakli, Berezinsky, Berezinsky, Berezinsky, Berezinsky, Bhattacharjee, Chung, D. Fargion, Dolgov, Dubrovich, Dubrovich, Ellis, Fargion, Fargion, Fargion, Fargion, Fargion, Felder, Feng, Fodor, Greisen, Hamaguchi, Hamaguchi, Kalashev, Khlopov, Khlopov, Khlopov, Khlopov, Khlopov, Khlopov, Kofman, Kusenko, Kuzmin, Kuzmin, Landau, Levitan, M.Yu. Khlopov, Okun, Sarkar, Sarkar, Spergel, Takeda, Tinyakov, V.K. Dubrovich, Weiler, Yoshida, Zatsepin, Ziaeepour   +49 more
core   +1 more source

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

FEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero, Maria Kopsida, Nathalie Arendt, Hans Lennernäs, Markus Sjöblom, Femke Heindryckx   +5 more
wiley   +1 more source

Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance

Aging and Cancer, EarlyView.
NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang, Zhong Fan, Runmeng Liu, Xiaotian Zhang   +3 more
wiley   +1 more source

Choroid Plexus Enlargement and USPIO‐Based Inflammatory Feature in Cerebral Small Vessel Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective The choroid plexus (CP) is a key component of the blood–cerebrospinal fluid barrier (BCSFB), but its mechanism of action in cerebral small vessel disease (CSVD) remains unclear. This study investigated CP volume (CPV) alterations and their association with conventional imaging markers in CSVD and explored the underlying role of ...
Yongqiang Qu, Xiaoning Ren, Cuihua Fan, Chun Li, Lijie Zhang, Zaiqiang Zhang, Shaowu Li, Zhongmeng Lai, Bin Cai, Ying Fu, Yi Lin, Zhibao Zhu   +11 more
wiley   +1 more source

Phase separation transition in anti-ferromagnetically interacting particle systems

, 2010
One dimensional non-equilibrium systems with short-range interaction can undergo phase transitions from homogeneous states to phase separated states as interaction ($\epsilon$) among particles is increased.
Kundu, Anasuya, Mohanty, P. K.
core   +1 more source

Developing and Evaluating a Laboratory‐Based Frailty Index for the Prediction of Long‐Term Health Outcomes in Systemic Lupus Erythematosus

Arthritis Care &Research, EarlyView.
Objective We aimed to construct and evaluate the first laboratory‐based frailty index (FI‐Lab) for predicting adverse outcomes in systemic lupus erythematosus (SLE) and to compare its predictive ability to that of an existing clinical FI. Methods We used data from a single‐center prospective cohort of adult patients with SLE whose baseline visit ...
Grace Burns, Samuel D. Searle, Alexandra Legge   +2 more
wiley   +1 more source

Temperature-based tuning of magnetic particle separation by on-chip free-flow magnetophoresis [PDF]

, 2009
This paper was presented at the 2nd Micro and Nano Flows Conference (MNF2009), which was held at Brunel University, West London, UK. The conference was organised by Brunel University and supported by the Institution of Mechanical Engineers, IPEM, the ...
2nd Micro and Nano Flows Conference (MNF2009), Iles, A, Pamme, N, Peyman, SA, Robert, D, Tarn, MD, Wilhelm, C   +6 more
core  

Probe for the strong parity violation effects at RHIC with three particle correlations

, 2008
In non-central relativistic heavy ion collisions, \P-odd domains, which might be created in the process of the collision, are predicted to lead to charge separation along the system orbital momentum \cite{Kharzeev:2004ey}.
A. M. Poskanzer, B. I. Abelev, D. E. Kharzeev, D. Kharzeev, D. Kharzeev, J. Adams, L. E. Finch, N. Borghini, S. A. Voloshin, S. A. Voloshin, S. A. Voloshin   +10 more
core   +1 more source

A Robust Adaptive One‐Sample‐Ahead Preview Super‐Twisting Sliding Mode Controller

International Journal of Adaptive Control and Signal Processing, EarlyView.
Block Diagram of the Robust Adaptive One‐Sample‐Ahead Preview Super‐Twisting Sliding Mode Controller. ABSTRACT This article introduces a discrete‐time robust adaptive one‐sample‐ahead preview super‐twisting sliding mode controller. A stability analysis of the controller by Lyapunov criteria is developed to demonstrate its robustness in handling both ...
Guilherme Vieira Hollweg, Paulo Jefferson Dias de Oliveira Evald, Shivam Chaturvedi, Hilton Abilio Gründling, Rodrigo Varella Tambara, Wencong Su   +5 more
wiley   +1 more source

3D-Printed Closed-Channel Spiral Inertial Microfluidic Device for Size-Based Particle Separation

Micromachines
Spiral inertial microfluidic devices provide a simple, high-throughput approach for size-based particle separation; however, translating PDMS-optimized designs into monolithic, fully enclosed 3D-printed channels is often limited by printability and post ...
Eda Ozyilmaz, Gamze Gediz Ilis
doaj   +1 more source