Results 31 to 40 of about 1,929 (230)

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

A hybrid chemical reaction-particle swarm optimisation technique for automatic generation control

open access: yesJournal of Electrical Systems and Information Technology, 2018
In this paper, a novel hybrid chemical reaction optimisation and particle swarm optimisation (HCROPSO) optimised PI controller has been proposed for automatic generation control (AGC) problem.
Banaja Mohanty, P.K. Hota
doaj   +1 more source

Conserved structural motifs in PAS, LOV, and CRY proteins regulate circadian rhythms and are therapeutic targets

open access: yesFEBS Letters, EarlyView.
Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman   +2 more
wiley   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

Optimisation of the hybrid renewable energy system by HOMER, PSO and CPSO for the study area

open access: yesInternational Journal of Sustainable Energy, 2017
This study is based on simulation and optimisation of the renewable energy system of the police control room at Sagar in central India. To analyse this hybrid system, the meteorological data of solar insolation and hourly wind speeds of Sagar in central ...
Vikas Khare   +2 more
doaj   +1 more source

Energy storage device locating and sizing based on power electronic transformer

open access: yesThe Journal of Engineering, 2019
In this study, firstly, the bi-directional energy flow of grid-connected photovoltaic and energy storage system based on power electronic transformer is demonstrated.
Qi Geng, Yan Hu
doaj   +1 more source

Stochastic stability of particle swarm optimisation [PDF]

open access: yesSwarm Intelligence, 2017
Particle swarm optimisation (PSO) is a metaheuristic algorithm used to find good solutions in a wide range of optimisation problems. The success of metaheuristic approaches is often dependent on the tuning of the control parameters. As the algorithm includes stochastic elements that effect the behaviour of the system, it may be studied using the ...
Adam Erskine   +2 more
openaire   +2 more sources

Cell wall target fragment discovery using a low‐cost, minimal fragment library

open access: yesFEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan   +5 more
wiley   +1 more source

Optimisation Methods for Cold Chain Logistics Path Considering Carbon Emission Costs in Time-Varying Networks

open access: yesPromet (Zagreb)
With the escalating global climate change, the cost of carbon emissions has become a crucial metric for evaluating the sustainability of logistics systems.
Zeyu WANG, Fujian CHEN, Chengcheng MO
doaj   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

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