Results 41 to 50 of about 76,865 (247)
Cell wall target fragment discovery using a low‐cost, minimal fragment library
FEBS Letters, EarlyView.LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
International Journal of Advanced Robotic Systems, 2019 Robots are coming to help us in different harsh environments such as deep sea or coal mine. Waste landfill is the place like these with casualty risk, gas poisoning, and explosion hazards.
Peng Chen +4 more
doaj +1 more source
Journal of Low Frequency Noise, Vibration and Active Control, 2020 Resolving the trade-offs between suspension travel, ride comfort, road holding, vehicle handling and power consumption is the primary challenge in the design of active vehicle suspension system. Multi-loop proportional + integral + derivative controllers’
Olurotimi A Dahunsi +3 more
doaj +1 more source
Curve-Fitting on Graphics Processors Using Particle Swarm Optimization [PDF]
International Journal of Computational Intelligence Systems, 2014 Curve fitting is a fundamental task in many research fields. In this paper we present results demonstrating the fitting of 2D images using CUDA (compute unified device architecture) on NVIDIA graphics processors via particle swarm optimization (PSO ...
R. T. Kneusel
doaj +1 more source
Machines, 2022 For the problem of defect inversion in magnetic flux leakage technology, a fast, globally convergent particle swarm optimization algorithm based on the finite-element forward model is introduced as an inverse iterative algorithm in this paper.
Senxiang Lu +3 more
doaj +1 more source
Design of Active Disturbance Rejection Controller for Dynamic Positioning Based on Improved Particle Swarm Optimization [PDF]
, 2022 Jia Hu, Wentao Chen
openalex +1 more source
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
Optimasi Decision Tree Menggunakan Particle Swarm Optimization untuk Klasifikasi Kesuburan pada Pria
Sistemasi: Jurnal Sistem Informasi, 2021 Abstrak Keturunan adalah hal yang sangat diharapkan pada setiap pasangan suami istri, maka dari itu tingkat kesuburan pada pria adalah salah satu faktor penting.
Tyas Widyani Pratiwi, Toni Arifin
doaj +1 more source
Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting
Molecular Oncology, EarlyView.CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia +9 more
wiley +1 more source
Molecular Oncology, EarlyView.HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto +13 more
wiley +1 more source