Results 51 to 60 of about 82,097 (301)

Feedback learning particle swarm optimization

, 2011
This is the author’s version of a work that was accepted for publication in Applied Soft Computing. Changes resulting from the publishing process, such as peer review, editing, corrections, structural formatting, and other quality control mechanisms may ...
Tang, Y, Zidong Wang, Wang, Z, Yang Tang, Fang, J, Jian-an Fang   +5 more
core   +1 more source

Interpreting the effects of DNA polymerase variants at the structural level

Molecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi, Karolina Krzesińska, Ludovica Beltrame, Pablo Sánchez‐Izquierdo Besora, Matteo Tiberti, Mef Nilbert, Anna Rohlin, Elena Papaleo   +7 more
wiley   +1 more source

Triggered memory-based swarm optimization in dynamic environments

, 2007
This is a post-print version of this article - Copyright @ 2007 Springer-VerlagIn recent years, there has been an increasing concern from the evolutionary computation community on dynamic optimization problems since many real-world optimization problems ...
Wang, H, Wang, X, Yang, S, Xingwei Wang (6019421), Hongfeng Wang, Shengxiang Yang, Dingwei Wang, Shengxiang Yang (7582940), Hongfeng Wang (1767415)   +8 more
core   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

Hybrid chaos-based particle swarm optimization-ant colony optimization algorithm with asynchronous pheromone updating strategy for path planning of landfill inspection robots

International Journal of Advanced Robotic Systems, 2019
Robots are coming to help us in different harsh environments such as deep sea or coal mine. Waste landfill is the place like these with casualty risk, gas poisoning, and explosion hazards.
Peng Chen, Qing Li, Chao Zhang, Jiarui Cui, Hao Zhou   +4 more
doaj   +1 more source

ZW4864‐mediated inhibition of the β‐catenin/BCL9/BCL9L complex reveals therapeutic potential in bladder cancer

Molecular Oncology, EarlyView.
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi, Mandy Berndt‐Paetz, Eileen Lerner, Gregoire Najjar, Anca Azoitei, Krishna Pal Singh, Shailendra Kumar Gupta, Olaf Wolkenhauer, Cagatay Günes, Otmar Huber, Marc‐Oliver Grimm, Daniel Steinbach   +11 more
wiley   +1 more source

Optimized Particle Swarm Optimization (OPSO) and its application to artificial neural network training

, 2006
Background: Particle Swarm Optimization (PSO) is an established method for parameter optimization. It represents a population-based adaptive optimization technique that is influenced by several "strategy parameters".
Meissner, Michael, Michael Schmuker (4736406), Schmuker Michael, Schneider, Gisbert (Prof. Dr.), Michael Meissner, Michael Schmuker, Gisbert Schneider, Schmuker, Michael, Gisbert Schneider (17096), Meissner Michael, Schneider Gisbert, Michael Meissner (17094)   +11 more
core   +1 more source

Building nearest prototype classifiers using a Michigan approach PSO [PDF]

, 2007
IEEE Swarm Intelligence Symposium. Honolulu, HI, 1-5 april 2007This paper presents an application of particle swarm optimization (PSO) to continuous classification problems, using a Michigan approach. In this work, PSO is used to process training data to
Galván, Inés M., Alejandro Cervantes, Pedro Isasi, Cervantes Rovira, Alejandro, Ines Galvan, Cervantes, Alejandro, Isasi, Pedro, Galván León, Inés María, Isasi Viñuela, Pedro   +8 more
core   +1 more source

A Fast Globally Convergent Particle Swarm Optimization for Defect Profile Inversion Using MFL Detector

Machines, 2022
For the problem of defect inversion in magnetic flux leakage technology, a fast, globally convergent particle swarm optimization algorithm based on the finite-element forward model is introduced as an inverse iterative algorithm in this paper.
Senxiang Lu, Jinhai Liu, Jing Wu, Xuewei Fu   +3 more
doaj   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei, Fredrik Orädd, Konstantinos Magkakis, Magnus Andersson   +3 more
wiley   +1 more source