Results 61 to 70 of about 2,957,454 (293)

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

open access: yesFEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei   +3 more
wiley   +1 more source

Hybrid chaos-based particle swarm optimization-ant colony optimization algorithm with asynchronous pheromone updating strategy for path planning of landfill inspection robots

open access: yesInternational Journal of Advanced Robotic Systems, 2019
Robots are coming to help us in different harsh environments such as deep sea or coal mine. Waste landfill is the place like these with casualty risk, gas poisoning, and explosion hazards.
Peng Chen   +4 more
doaj   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

open access: yesFEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli   +8 more
wiley   +1 more source

Refinement of amino‐acid conformation vs. difference density maps in time‐resolved serial femtosecond crystallography data analysis

open access: yesFEBS Open Bio, EarlyView.
The dFoCC pipeline starts with observed DED and resting‐state coordinates, which are then used to generate a library of triggered states. Correlation analysis of the calculated DED features of each candidate vs observed DED permits quantitative evaluation of candidate structural quality.
Meng Iao Fong   +3 more
wiley   +1 more source

Proportional + integral + derivative control of nonlinear full-car electrohydraulic suspensions using global and evolutionary optimization techniques

open access: yesJournal of Low Frequency Noise, Vibration and Active Control, 2020
Resolving the trade-offs between suspension travel, ride comfort, road holding, vehicle handling and power consumption is the primary challenge in the design of active vehicle suspension system. Multi-loop proportional + integral + derivative controllers’
Olurotimi A Dahunsi   +3 more
doaj   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

open access: yesFEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova   +2 more
wiley   +1 more source

Multi-Exemplar Particle Swarm Optimization

open access: yesIEEE Access, 2020
PSO and its variants have proven to be useful algorithms for tackling a wide range of optimization problems in recent decades. However, PSO and most of its variants only consider the influences caused by global best position and personal historical best ...
Wei Song, Ziyu Hua
doaj   +1 more source

Curve-Fitting on Graphics Processors Using Particle Swarm Optimization [PDF]

open access: yesInternational Journal of Computational Intelligence Systems, 2014
Curve fitting is a fundamental task in many research fields. In this paper we present results demonstrating the fitting of 2D images using CUDA (compute unified device architecture) on NVIDIA graphics processors via particle swarm optimization (PSO ...
R. T. Kneusel
doaj   +1 more source

Identification of (20R)‐protopanaxadiol from Panax ginseng as a novel anti‐SARS‐CoV‐2 compound

open access: yesFEBS Open Bio, EarlyView.
We established a noninfectious BAC‐based SARS‐CoV‐2 replicon that enables antiviral screening under BSL‐2 conditions. Using this platform, we screened 373 food‐derived compounds and identified (20R)‐protopanaxadiol from Panax ginseng as a novel inhibitor of SARS‐CoV‐2 RNA replication, highlighting the value of safe replicon systems for antiviral ...
Midori Takeda   +4 more
wiley   +1 more source

A clustering particle swarm optimizer for dynamic optimization [PDF]

open access: yes, 2009
This article is posted here with permission of the IEEE - Copyright @ 2009 IEEEIn the real world, many applications are nonstationary optimization problems.
Yang, S   +5 more
core   +1 more source

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