Results 51 to 60 of about 165,169 (251)
FEBS Letters, EarlyView.Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman +2 more
wiley +1 more source
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
FEBS Letters, EarlyView.We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
Firefly Algorithms for Multimodal Optimization [PDF]
, 2009 Nature-inspired algorithms are among the most powerful algorithms for optimization. This paper intends to provide a detailed description of a new Firefly Algorithm (FA) for multimodal optimization applications.
Yang, Xin-She
core +1 more source
Cell wall target fragment discovery using a low‐cost, minimal fragment library
FEBS Letters, EarlyView.LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
Machines, 2022 For the problem of defect inversion in magnetic flux leakage technology, a fast, globally convergent particle swarm optimization algorithm based on the finite-element forward model is introduced as an inverse iterative algorithm in this paper.
Senxiang Lu +3 more
doaj +1 more source
Improved dynamical particle swarm optimization method for structural dynamics [PDF]
, 2019 A methodology to the multiobjective structural design of buildings based on an improved particle swarm optimization algorithm is presented, which has proved to be very efficient and robust in nonlinear problems and when the optimization objectives are in
Annicchiarico, W. C. +1 more
core +2 more sources
Structural biology of ferritin nanocages
FEBS Letters, EarlyView.Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
International Journal of Advanced Robotic Systems, 2019 Robots are coming to help us in different harsh environments such as deep sea or coal mine. Waste landfill is the place like these with casualty risk, gas poisoning, and explosion hazards.
Peng Chen +4 more
doaj +1 more source
Journal of Low Frequency Noise, Vibration and Active Control, 2020 Resolving the trade-offs between suspension travel, ride comfort, road holding, vehicle handling and power consumption is the primary challenge in the design of active vehicle suspension system. Multi-loop proportional + integral + derivative controllers’
Olurotimi A Dahunsi +3 more
doaj +1 more source