Results 101 to 110 of about 3,630,144 (297)

Optimization of seminal extracellular vesicle isolation protocols for cancer biomarker analysis using proteomic profiling

Molecular Oncology, EarlyView.
This paper shows that size‐exclusion chromatography and sequential centrifugation applied to seminal plasma enrich for different populations of extracellular vesicles. This may significantly affect the detection and analysis of extracellular vesicle‐associated cancer biomarkers.
Elen Telumyan, Beatriz Martín‐Gracia, Eva Bassols‐Citores, Krizia Sagini, Maria K. Andersen, Tuula A. Nyman, May‐Britt Tessem, Morten B. Rye, Alicia Llorente   +8 more
wiley   +1 more source

Turbulent particle pinch in gyrokinetic flux-driven ITG/TEM turbulence

Nuclear Fusion
Aiming at a fuel supply through particle pinch effects, turbulent particle transport is studied by gyrokinetic flux-driven Ion-Temperature-Gradient/Trapped-Electron-Mode (ITG/TEM) simulations.
Kenji Imadera, Yasuaki Kishimoto, Akihiro Ishizawa   +2 more
doaj   +1 more source

The multifaceted roles of lysosomes in cancer

Molecular Oncology, EarlyView.
Lysosomes support cancer cell adaptation by integrating macromolecule degradation and nutrient recycling with nutrient sensing, inter‐organelle communication and immune regulation. These interconnected functions can promote tumour growth, stress tolerance and therapy resistance, while also creating context‐dependent vulnerabilities that may be ...
Jia Li, Kevin M. Ryan
wiley   +1 more source

USP7 inhibits FOXO1 activity in chronic lymphocytic leukaemia cells enhancing cell survival

Molecular Oncology, EarlyView.
CLL cells rely on BCR‐mediated signalling for survival and proliferation in part through suppression of FOXO1. FOXO1 activity is regulated by a plethora of post‐translational modifications including phosphorylation and ubiquitination. We demonstrated that dual inhibition of BCR signalling and the deubiquitinase USP7 activates FOXO1, modulating its ...
Hassan N.B. Almuhanna, Jodie Hay, Michael W. Moles, Lucy Clarke, Jennifer Cassels, Alison Sefcick, Alison M. McCaig, Heather G. Jørgensen, Alison M. Michie   +8 more
wiley   +1 more source

Optimal conditions for indoor air purification using non-thermal Corona discharge electrostatic precipitator

Open Physics
Cold plasmas improve indoor air quality by reducing fine and ultrafine particles threatening human health. Electrostatic precipitator (ESP) uses non-thermal corona discharge connected to negative DC high voltage needles with grounded parallel plate ...
Elaissi Samira, Alsaif Norah A.M., Moneer Eman M., Gouadria Soumaya   +3 more
doaj   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source

Computational fluid dynamics modeling of aerosol particle transport through lung airway mucosa. [PDF]

Comput Chem Eng, 2023
Bartlett BA, Feng Y, Fromen CA, Ford Versypt AN.   +3 more
europepmc   +1 more source

Transport of citrate in submitochondrial particles [PDF]

FEBS Letters, 1977
Prezioso, G., Stipani, I., Palmieri, F., Quagliariello, E.   +3 more
openaire   +2 more sources

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

FEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard, Emma‐Jayne Proctor, Jiawa Wang, Nikolas P. Johnston, Andrew Hayes, Georgia McCorkell, Haibo Yu, Jai Tree, Mark R. Davies, Mark J. Walker, Ronald Sluyter, Stephan Brouwer, Martina L. Sanderson‐Smith   +12 more
wiley   +1 more source

Liquid Fragmentation Induced by Particle Aggregation During Two‐Phase Flow in 3D Porous Media

Geophysical Research Letters
Natural or engineered microparticles are often encountered in subsurface multiphase flow systems. This introduces a complex flow scenario with a variety of applications.
Ting Wu, Zhibing Yang, Alizée Lehoux, Noam Weisbrod, Ran Hu, Yi‐Feng Chen, Ya‐An Hu   +6 more
doaj   +1 more source