Results 91 to 100 of about 223,851 (268)

Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance

Aging and Cancer, EarlyView.
NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang, Zhong Fan, Runmeng Liu, Xiaotian Zhang   +3 more
wiley   +1 more source

A 20:1 synergetic mixture of cafedrine/theodrenaline accelerates particle transport velocity in murine tracheal epithelium via IP₃ receptor-associated calcium release. [PDF]

Front Pharmacol, 2023
Schmidt G, Rienas G, Müller S, Edinger F, Sander M, Koch C, Henrich M.   +6 more
europepmc   +1 more source

Predicting Loss of Ambulation in Limb Girdle Muscular Dystrophy R9

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Limb girdle muscular dystrophy type R9 (LGMDR9) results from biallelic variants in FKRP. There is limited data to predict loss of ambulation (LOA) among those with LGMDR9. Methods Participants in an ongoing dystroglycanopathy natural history study (NCT00313677) with FKRP variants who had achieved ambulation and were more than 3 ...
Chandra L. Miller, Lauren N. Coffey, Shelley R. H. Mockler, Katie M. Laubscher, Carrie M. Stephan, M. Bridget Zimmerman, Katherine D. Mathews   +6 more
wiley   +1 more source

How tracer particles sample the complexity of turbulence

New Journal of Physics, 2018
On their roller coaster ride through turbulence, tracer particles sample the fluctuations of the underlying fields in space and time. Quantitatively relating particle and field statistics remains a fundamental challenge in a large variety of turbulent ...
Cristian C Lalescu, Michael Wilczek
doaj   +1 more source

A scaling law of particle transport in inkjet-printed particle-laden polymeric drops. [PDF]

Int J Heat Mass Transf, 2022
Cheng C, Jae Moon Y, Hwang JY, Chiu GT, Han B.   +4 more
europepmc   +1 more source

β‐Catenin/c‐Myc Axis Modulates Autophagy Response to Different Ammonia Concentrations

Advanced Biology, Volume 9, Issue 3, March 2025.
Ammonia, detoxified by the liver into urea and glutamine, impacts autophagy differently at varying levels. Low ammonia activates autophagy via c‐Myc and β‐catenin, while high levels suppress it. Using Huh7 cells and Spf‐ash mice, c‐Myc's role in cytoprotective autophagy is revealed, offering insights into hyperammonemia and potential therapeutic ...
S. Sergio, B. Spedicato, G. Corallo, A. Inguscio, M. Greco, D. Musarò, D. Vergara, A. F. Muro, G. De Sabbata, L. R. Soria, N. Brunetti Pierri, M. Maffia   +11 more
wiley   +1 more source

Coverable Self‐Cleaning Glass via Abnormal Transport and Jump of Charged Particles

Advanced Science
Surface particle pollution is present everywhere, from windows in daily life to transparent curtain walls in tall buildings and photovoltaic panels in deserts.
Meng Yang, Conglin Li, Wei Tang, Wenchao Gao, Weiguo Weng, Yingchun Wu, Yifan Wang, Chenghang Zheng, Xiang Gao   +8 more
doaj   +1 more source

Spatial configuration of charge and hydrophobicity tune particle transport through mucus. [PDF]

Biophys J, 2022
Samad T, Witten J, Grodzinsky AJ, Ribbeck K.   +3 more
europepmc   +1 more source

Mechanochemical Synthesis and Characterization of Nanostructured ErB4 and NdB4 Rare‐Earth Tetraborides

Advanced Engineering Materials, Volume 27, Issue 6, March 2025.
ErB4 and NdB4 nanostructured powders are produced by mechanochemical synthesis. 5 h mechanical alloying and 4 M HCl acid leaching are used in the production. ErB4 and NdB4 powders exhibit maximum magnetization of 0.4726 emu g−1 accompanied with an antiferromagnetic‐to‐paramagnetic phase transition at about TN = 18 K and 0.132 emu g−1 with a maximum at ...
Burçak Boztemur, Faruk Kaya, Bora Derin, Mustafa Lütfi Öveçoğlu, Ju Li, Duygu Ağaoğulları   +5 more
wiley   +1 more source

Towards understanding respiratory particle transport and deposition in the human respiratory system: Effects of physiological conditions and particle properties. [PDF]

J Hazard Mater, 2022
Yao Z, Zhao T, Su W, You S, Wang CH.
europepmc   +1 more source