Results 71 to 80 of about 3,630,144 (297)

3D Lagrangian Particle Tracking

open access: yes, 2021
3D Lagrangian Particle Tracking (LPT) is an image-based flow measurement technique allowing to determine position, velocity and acceleration along a large number of particle tracks at high temporal resolution within the investigated volume.
Novara, Matteo   +4 more
core  

Smaller is better: nanobodies meet NMR

open access: yesFEBS Letters, EarlyView.
Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley   +1 more source

Going viral − Virus‐targeting nanobodies for research, diagnostics and therapy

open access: yesFEBS Letters, EarlyView.
The increasing prevalence of viral diseases represents a major threat for global human health. Nanobodies, small binding fragments derived from camelid heavy‐chain antibodies, offer versatile tools for viral research, diagnostics, and antiviral therapy.
Domenic Ebert, Ulrich Rothbauer
wiley   +1 more source

Geochemical Influences on Carbon Nanotubes Transport in Subsurface Environments: Integrating Millifluidics, Spectral Induced Polarization, and Machine Learning

open access: yesGeophysical Research Letters
Understanding nanoparticles, like carbon nanotube (CNT), transport and retention in porous media is critical for environmental risk assessment and remediation. Millifluidic visualization, spectral induced polarization (SIP), and deep neural network (DNN)
Yixin Yang   +7 more
doaj   +1 more source

Soft motions encoded by the fold and mediated by conserved hinge sites drive V‐ATPase allosteric machinery and autoinhibition

open access: yesFEBS Letters, EarlyView.
Vacuolar H+‐ATPase (V‐ATPase) is a multisubunit rotary proton pump that acidifies intracellular compartments. Using elastic network models, we identified conserved hinge residues that govern its large‐scale functional motions. We show that intrinsically encoded ‘soft modes’ drive critical functional transitions, including rotary catalysis and ...
Diksha Parwana   +3 more
wiley   +1 more source

The Future of Interurban Passenger Transport: Bringing Citizens Closer Together - 18th International Symposium on Transport Economics and Policy [PDF]

open access: yes, 2010
The Symposium brought together leading transport researchers from around the world to explore a range of issues under the general theme of “the future for interurban passenger transport”.
OECD, International Transport Forum
core   +1 more source

Unlocking the potential of cell‐permeable nanobodies for intracellular applications

open access: yesFEBS Letters, EarlyView.
This review outlines current strategies for delivery of nanobodies into cells and highlights recent examples of functional applications. By addressing and manipulating intracellular targets, these molecules hold great potential for treating cancer, respiratory diseases and neurological disorders, making this a vibrant area of research in the biomedical
Mariona Gené‐Verdés   +2 more
wiley   +1 more source

Comparing the paths of Hedgehog release in artificial and natural settings

open access: yesFEBS Letters, EarlyView.
Hh morphogens require solubilization factors to overcome their tight association with the plasma membrane and signal to distant cells, but the precise functions of these factors are controversial. Here, we use published in vivo observations as the most relevant evidence to test their suggested functions and discuss contradictions and gaps between in ...
Janna Puschmann, Kay Grobe
wiley   +1 more source

Monitoring sand particle concentration in multiphase flow using acoustic emission technology [PDF]

open access: yes, 2014
Multiphase flow is the simultaneous flow of two or several phases through a system such as a pipe. This common phenomenon can be found in the petroleum and chemical engineering industrial fields.
El-Alej, Mohamed Essid
core   +4 more sources

Mitochondrial translation and coordinated cytosolic translation in metabolic homeostasis and disease

open access: yesFEBS Letters, EarlyView.
Mitochondrial function depends on coordinated protein production from the nuclear and mitochondrial genomes. This review highlights how cytosolic and mitochondrial translation, mRNA localization, protein import, and respiratory complex assembly are integrated to maintain mitochondrial proteostasis and function.
Boseon Kim   +4 more
wiley   +1 more source

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