Results 71 to 80 of about 223,851 (268)

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei, Fredrik Orädd, Konstantinos Magkakis, Magnus Andersson   +3 more
wiley   +1 more source

Chameleon sequences reveal structural effects in proteins representing micelle‐like distribution of hydrophobicity

FEBS Open Bio, EarlyView.
Amino acids sequence of two different proteins with the same sequence (chameleon sequence—black boxes) represent in 3D structure of the proteins different secondary structures: HHHH—helical and BBB—Beta‐structural. The chains folded in water environment adopt different III‐order structures in which the chameleon fragments appear to adopt similar status
Irena Roterman, Katarzyna Stapor, Leszek Konieczny, Krzysztof Gądek, Piotr Nowakowski   +4 more
wiley   +1 more source

Exon 7 splicing of ERα predicts poor prognosis and increases phenotypic heterogeneity in luminal a subtype breast cancer

FEBS Open Bio, EarlyView.
ERα splice variant ERα∆7 lacks the C‐terminus, and its expression may change phenotypes of breast cancers. Our results showed that ERα∆7 is found in the luminal A subtype, and elevated ERα∆7 levels are linked to improved cell survival with lower proliferation and migration.
Long Wai Tsui, Taobo Hu, Thomson Christian Husein, Wai Hei Shek, Bingrong Chen, Depeng Wang, Shu Wang, Weichuan Yu, Xiaodan Fan, Mengping Long, Toyotaka Ishibashi   +10 more
wiley   +1 more source

Turbulent particle pinch in gyrokinetic flux-driven ITG/TEM turbulence

Nuclear Fusion
Aiming at a fuel supply through particle pinch effects, turbulent particle transport is studied by gyrokinetic flux-driven Ion-Temperature-Gradient/Trapped-Electron-Mode (ITG/TEM) simulations.
Kenji Imadera, Yasuaki Kishimoto, Akihiro Ishizawa   +2 more
doaj   +1 more source

Computational fluid dynamics modeling of aerosol particle transport through lung airway mucosa. [PDF]

Comput Chem Eng, 2023
Bartlett BA, Feng Y, Fromen CA, Ford Versypt AN.   +3 more
europepmc   +1 more source

Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function

FEBS Open Bio, EarlyView.
We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke, Michal Banasik, Rokas Juodeikis, Martin J. Warren, Richard W. Pickersgill   +4 more
wiley   +1 more source

Correlated particle transport enables biological free energy transduction. [PDF]

Biophys J, 2023
Terai K, Yuly JL, Zhang P, Beratan DN.
europepmc   +1 more source

Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum

FEBS Open Bio, EarlyView.
Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik, Russell Pickford, Hannah C. Timmins, Olivier Piguet, Glenda M. Halliday, Matthew C. Kiernan, Woojin Scott Kim   +6 more
wiley   +1 more source

Liquid Fragmentation Induced by Particle Aggregation During Two‐Phase Flow in 3D Porous Media

Geophysical Research Letters
Natural or engineered microparticles are often encountered in subsurface multiphase flow systems. This introduces a complex flow scenario with a variety of applications.
Ting Wu, Zhibing Yang, Alizée Lehoux, Noam Weisbrod, Ran Hu, Yi‐Feng Chen, Ya‐An Hu   +6 more
doaj   +1 more source

Canopy-Mediated Hydrodynamics Contributes to Greater Allelic Richness in Seeds Produced Higher in Meadows of the Coastal Eelgrass Zostera marina

Frontiers in Marine Science, 2019
Seagrass meadows, which mediate ocean acidity and turbidity, sequester carbon, and increase biodiversity by providing shelter for larvae and small fish, are among the fastest disappearing ecosystems worldwide. Seagrasses are ecosystem engineers, creating
Elizabeth Follett, Cynthia G. Hays, Heidi Nepf   +2 more
doaj   +1 more source