Results 51 to 60 of about 3,434,853 (290)
Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis
FEBS Letters, EarlyView.Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee +7 more
wiley +1 more source
Improved modelling of SEP event onset within the WSA–Enlil–SEPMOD framework
Journal of Space Weather and Space ClimateMulti-spacecraft observations of solar energetic particle (SEP) events not only enable a deeper understanding and development of particle acceleration and transport theories but also provide important constraints for model validation efforts.
Palmerio Erika +16 more
doaj +1 more source
Physics, 2022 In this paper, the effects of wave–wave interactions of the lowest order, i.e., three-wave interactions, on parallel-propagating Alfvén wave spectra on a closed magnetic field line are considered.
Seve Nyberg, Rami Vainio
doaj +1 more source
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
FEBS Letters, EarlyView.The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
Study on microstructure and properties of pure tantalum TIG joints
Hanjie xuebaoA study on the microstructure, mechanical properties, and heat treatment process of pure tantalum TIG joints was conducted. Industrial computed tomography (CT), OM, and SEM were used to characterize the microstructure of the joints, and a microhardness ...
Chao YAN +3 more
doaj +1 more source
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
Modeling the transport and anisotropy of energetic electrons in solar flares
Frontiers in Astronomy and Space SciencesTransport of energetic electrons in the flare loop is important to understanding nonthermal emissions in solar flares. In this work, we model the propagation of electrons by numerically solving the particle transport equation which includes the physics ...
Xiangliang Kong +5 more
doaj +1 more source
Modelling of Nanoparticle Distribution in a Spherical Tumour during and Following Local Injection
Pharmaceutics, 2022 Radio-sensitizing nanoparticles are a potential method to increase the damage caused to cancerous cells during the course of radiotherapy. The distribution of these particles in a given targeted tumour is a relevant factor in determining the efficacy of ...
George Caddy +3 more
doaj +1 more source
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
FEBS Letters, EarlyView.Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
Effect of Slide Valve Gap Surface Roughness on Particle Transport Properties
AerospaceFuel electro-hydraulic servo valves are core components in the fuel control system of aero-engines, and their performance directly affects thrust regulation and power output precision.
Jin Zhang +6 more
doaj +1 more source