Results 41 to 50 of about 4,224,729 (260)

Efficacy and Tolerability of Topotecan/Cyclophosphamide/Dinutuximab in Relapsed and Refractory High‐Risk Neuroblastoma: A Multi‐Institutional Retrospective Study

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Purpose Chemoimmunotherapy with irinotecan, temozolomide, and dinutuximab (I/T/DIN) has emerged as first‐line therapy for relapsed/refractory (r/r) high‐risk neuroblastoma (HRNB) in North America. Topotecan and cyclophosphamide (T/C) are often used in combination with dinutuximab in the setting of lack of response, progression, or incomplete ...
Benjamin J. Lerman   +17 more
wiley   +1 more source

ASABİYET VE KARDEŞLİK: TİKEL-TÜMEL İLİŞKİSİ?

open access: yesFelsefe Dünyası, 2011
Bu yazıda, İbn Haldun’un Mukaddime’de daha çok siyasi içerikli bir kavramolarak kullandığı, insanların toplum halinde yaşaması olgusunu temellendirmektesıklıkla başvurduğu ve soy ve neden asabiyeti olarak iki kategorideincelediği asabiyet kavramıyla, 18.
H. Fırat Şenol
doaj  

Clinical Course and Impact of Breaks in Therapy for Children With Relapsed/Refractory Solid Tumors

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Introduction Pediatric relapsed or refractory (R/R) solid tumors carry a dismal prognosis, and postrelapse patient experiences are not well described. We present postrelapse outcomes, including number of R/R events and subsequent therapy regimens.
Matthew T. McEvoy   +5 more
wiley   +1 more source

Consideraciones hermenéuticas y metodología para la elaboración del material educativo impreso en la modalidad a distancia / Hermeneutical and methodological considerations for the elaboration of printed educational materials in distance learning studies

open access: yesSophía: Colección de Filosofía de la Educación, 2013
Si bien las Tecnologías de la Información y Comunicación (TIC) se han constituido en un pilar fundamental de la educación en general y, especialmente en el proceso de enseñanza-aprendizaje de la educación a distancia, la mayoría de instituciones que ...
Elsa Beatriz Cárdenas Sempértegui   +4 more
doaj   +1 more source

Particulars

open access: yesCoSMO, 2021
Until half a century ago, the question “what is literature?” was common in literary studies. Today such questions have something naïve, especially in a time that has become sceptical towards theories. This article tries to avoid this naïve side starting from two books that have enquired into the question ‘what is literature’, in an analytical and ...
openaire   +2 more sources

Molecular Methods for Rare Hemoglobinopathy Cases: First Brazilian Report of Pediatric Siblings with Hb O‐Arab and Alpha‐Thalassemia

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Hemoglobinopathies are prevalent globally; diagnosis is complex in high genetic admixture populations like Brazil. We report, in two pediatric siblings, the first documented cases in Brazil of heterozygosity for hemoglobin (Hb) O‐Arab with coinheritance of α‐thalassemia (αα/−α4.2; −α3.7/−α4.2), resulting in microcytic and hypochromic anemia ...
Elisângela de Souza Miranda Muynarsk   +9 more
wiley   +1 more source

Transient Particulars

open access: yesErgo an Open Access Journal of Philosophy
We spend much of our adult lives thinking and reminiscing about particular events of the past, which, by their very nature, can never be repeated. What is involved in a capacity to think thoughts of this kind? In this paper, I propose that such thoughts are essentially connected with a capacity to communicate about past events, and specifically in the ...
openaire   +3 more sources

Criterion‐Related Validity of the Neuropsychological Quick Assessment for Screening Cognitive, Motor, and Behavioral Impairments in Patients With Pediatric Brain Tumors: An Observational Pilot Study

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Neuropsychological complications may impair the qualitative prognosis of patients with pediatric brain tumors. However, multifaceted evaluations cannot be conducted in all patients because they are time consuming and burdensome for patients.
Ami Tabata   +9 more
wiley   +1 more source

The Efficacy and Safety of Bevacizumab/Irinotecan/Temozolomide (BIT) for Relapsed/Refractory Neuroblastoma: The UK Children's Cancer and Leukaemia Group Experience

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Patients with high‐risk neuroblastoma who either are refractory to induction chemotherapy or relapse following multi‐modal treatment have a dismal prognosis. Based on data from the BEACON trial, since 2021 the UK national guidelines recommend bevacizumab, irinotecan, and temozolomide (BIT) for patients with relapsed/refractory ...
Thomas J. Jackson   +20 more
wiley   +1 more source

A mecânica da ordem: individuo e sociedade em Durkheim

open access: yesCadernos de Campo, 2003
O artigo analisa brevemente a relação entre indivíduo e Sociedade a partir da sociologia de Durkheim, bem como considera criticamente as implicações dessa polaridade em termos de determinação do sujeito.
Edison Bariani Júnior
doaj  

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