Results 91 to 100 of about 5,357 (285)
The process of microRNAs discovery
Zagadnienia Filozoficzne w Nauce, 2020 The widespread particularist account of the onset of molecular biology that identifies it with the discovery of the DNA structure in 1953 has been recently contested.
Paweł Kawalec
doaj
Eklezja siostrzana a realizm Kościoła partykularnego
Studia Koszalińsko-Kołobrzeskie, 2016 Every celebrations connected with baptism, including current rounds 1050 – of anniversary in Poland, should remind everyone baptized about their participation in the universal and endless value.
Jarosław Moskałyk
doaj +1 more source
DNA ligase LigE increases bacterial transformation with damaged extracellular DNA
FEBS Letters, EarlyView.The DNA ligase LigE from the naturally competent Gram‐negative bacterium Neisseria gonorrhoaea increases transformation with cut extracellular DNA. This process is ATP‐dependent and relies on the catalytic activity of LigE; it also requires that LigE contains an intact periplasmic localisation sequence, indicating that ligE functions in the periplasm ...
Jolyn Pan +4 more
wiley +1 more source
, 2010 According to the standard view of particularity, an entity is a particular just in case it necessarily has a unique spatial location at any time of its existence. That the basic entities of the world we speak about in common sense and science are particular entities in this sense is the thesis of foundational particularism, a theoretical intuition that
openaire +3 more sources
Unlocking the potential of cell‐permeable nanobodies for intracellular applications
FEBS Letters, EarlyView.This review outlines current strategies for delivery of nanobodies into cells and highlights recent examples of functional applications. By addressing and manipulating intracellular targets, these molecules hold great potential for treating cancer, respiratory diseases and neurological disorders, making this a vibrant area of research in the biomedical
Mariona Gené‐Verdés +2 more
wiley +1 more source
Comparing the paths of Hedgehog release in artificial and natural settings
FEBS Letters, EarlyView.Hh morphogens require solubilization factors to overcome their tight association with the plasma membrane and signal to distant cells, but the precise functions of these factors are controversial. Here, we use published in vivo observations as the most relevant evidence to test their suggested functions and discuss contradictions and gaps between in ...
Janna Puschmann, Kay Grobe
wiley +1 more source
Molecular Oncology, EarlyView.Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur +11 more
wiley +1 more source
Combining Phenomenology and Moral Particularism: A Trilemma of Moral Truth
, 2020 Discusses that Moral Particularism and Moral Phenomenology require one another, and that this requirement may have some inconsistencies when given full consideration to their implications.
Arriaga, Alejandro
core