Results 91 to 100 of about 3,459 (300)

Hannah Arendt: Jew and Cosmopolitan

open access: yesSocio, 2015
This paper deals with the difference between universalism and cosmo-politanism. If I understand correctly, what makes cosmopolitanism distinctive is that it is always rooted in a specific identity which realizes that it is specific, and always endeavours
Natan Sznaider
doaj   +1 more source

Particulars

open access: yesCoSMO, 2021
Until half a century ago, the question “what is literature?” was common in literary studies. Today such questions have something naïve, especially in a time that has become sceptical towards theories. This article tries to avoid this naïve side starting from two books that have enquired into the question ‘what is literature’, in an analytical and ...
openaire   +2 more sources

Combining Phenomenology and Moral Particularism: A Trilemma of Moral Truth

open access: yes, 2020
Discusses that Moral Particularism and Moral Phenomenology require one another, and that this requirement may have some inconsistencies when given full consideration to their implications.
Arriaga, Alejandro
core  

MITF maintains genome stability in nonmelanocyte lineages

open access: yesMolecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir   +13 more
wiley   +1 more source

On Deontic Truth and Values

open access: yesCrítica, 2018
This article analyzes the thesis of ethical relativism, as defended by Alchourrón and Bulygin (1983). These authors offer, on the one hand, a suggestive conception according to which the question “what are our obligations?” is equivalent to thinking ...
J. J. Moreso
doaj   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

Universalism and particularism: philosophical discussions about researching of conspiracy beliefs

open access: yesИнтеллект. Инновации. Инвестиции
In this article, the authors review current philosophical discussions about the essence and specific features of conspiracy beliefs, the purpose of which is to formulate its relevant definitions.
A. V. Dumov, V. I. Kudashov
doaj   +1 more source

Values Underlying the Information Culture in Communist and Post-Communist Russia (1917−1999)

open access: yesMedia and Communication, 2015
In this article the concept of information culture—understood as the dominant handling of information, shared by a dominant proportion of journalists, the public, authorities and other actors within a societal environment at a given time and place—is ...
Hedwig de Smaele
doaj   +1 more source

Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma

open access: yesMolecular Oncology, EarlyView.
Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski   +10 more
wiley   +1 more source

The process of microRNAs discovery

open access: yesZagadnienia Filozoficzne w Nauce, 2020
The widespread particularist account of the onset of molecular biology that identifies it with the discovery of the DNA structure in 1953 has been recently contested.
Paweł Kawalec
doaj  

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