Results 71 to 80 of about 97,880 (262)

EpCAM+ Extracellular Vesicle PD‐L1 Dynamics as a Predictive Biomarker of Immune Checkpoint Blockade Response

Advanced Science, EarlyView.
A highly sensitive SERS‐based platform measures PD‐L1 expression on EpCAM+ circulating EVs from cancer patients undergoing immunotherapy. Monitoring dynamic changes after treatment reveals that reduced EpCAM+ EV PD‐L1 levels associate with improved long‐term clinical outcomes, establishing a non‐invasive approach for tracking immune checkpoint ...
Byeonggeol Mun, Jinyoung Kim, Chang Gon Kim, Seokhyeong Go, Mina Han, Yujin Ouck, Soojin Jang, Seong Uk Son, Gamin Kim, Wonrak Son, Eunjung Kim, Min Hee Hong, Ja Hyun Yeo, Eun‐Kyung Lim, Hye Ryun Kim, Seungjoo Haam   +15 more
wiley   +1 more source

Mechanical Flexibility Enables DNA Origami to Overcome Steric Confinement in Mucus

Advanced Science, EarlyView.
Mechanical flexibility is introduced as a design parameter to enhance nanocarrier transport in mucus. Using DNA origami, flexibility is decoupled from size, shap and surface chemistry, revealing improved passage through confined hydrogel networks. While surface passivation reduces aggregation, flexibility further boosts transport, offering a general ...
Matteo Tollemeto, Emily Tsang, Marie Karen Tracy Hong Lin, Luca Mannino, Kurt V. Gothelf, Anja Boisen   +5 more
wiley   +1 more source

Characteristics of Vehicle Tire and Road Wear Particles’ Size Distribution and Influencing Factors Examined via Laboratory Test

Atmosphere
With the implementation of strict emission regulations and the use of cleaner fuels, there has been a considerable reduction in exhaust emissions. However, the relative contribution of tire wear particles (TWPs) to particulate matters is expected to ...
Chongzhi Zhong, Jiaxing Sun, Jing Zhang, Zishu Liu, Tiange Fang, Xiaoyu Liang, Jiawei Yin, Jianfei Peng, Lin Wu, Qijun Zhang, Hongjun Mao   +10 more
doaj   +1 more source

Particulate Matter Matters

, 2019
For the second time, the Data Science Challenge took place as part of the 18th symposium “Database Systems for Business, Technology and Web” (BTW) of the Gesellschaft für Informatik (GI). The Challenge was organized by the University of Rostock and sponsored by IBM and SAP.
Meyer, Holger J., Gruner, Hannes, Waizenegger, Tim, Woltmann, Lucas, Hartmann, Claudio, Lehner, Wolfgang, Esmailoghli, Mahdi, Redyuk, Sergey, Martinez, Ricardo, Abedjan, Ziawasch, Ziehn, Ariane, Rabl, Tilmann, Markl, Volker, Schmitz, Christian, Serai, Dhiren Devinder, Gava, Tatiane Escobar   +15 more
openaire   +1 more source

Microenvironment‐Responsive Nanomedicine Enables Vertical Modulation of Mitochondrial Pathological Networks in Myocardial Ischemia–Reperfusion Injury

Advanced Science, EarlyView.
A mitochondria‐targeted, microenvironment‐responsive nanoplatform enables pH/ROS‐triggered co‐delivery of berberine and isoliensinine to orchestrate ROS scavenging, inflammation suppression, and apoptosis inhibition. This vertical modulation of mitochondrial pathological networks preserves mitochondrial function and effectively mitigates myocardial ...
Jue Wang, Jia Zhou, Wenqin Yuan, Tianjiao Zhao, Yunying Huang, Yingci Xia, Yuting Lin, Fei Li, Qiong Huang, Chong Liu, Kelong Ai, Qun Qin   +11 more
wiley   +1 more source

Particulate matter in bubble oxygenators

The Journal of Thoracic and Cardiovascular Surgery, 1974
The degree of contamination was evaluated in seven blood oxygenators in common use. The Bentley Q 100 unit was found to have the highest degree of particulate contamination and the Travenol 6LF the lowest. Evidence is presented in favor of adopting a micropore filtration and washing technique of the bubble oxygenator immediately before open-heart ...
C C, Reed, A, Romagnoli, D E, Taylor, D K, Clark   +3 more
openaire   +2 more sources

Ti‐Doping Activates Adjacent Zr Sites in Bimetallic MOFs for Cooperative Phospholipid Removals in Human Biomonitoring

Advanced Science, EarlyView.
Ti‐doped Zr/Ti bimetallic MOFs activate neighboring Zr sites to selectively capture phospholipids from serum through cooperative interactions. In nontargeted screening, the material minimizes matrix interference, expands detectable feature coverage, and enables broad recovery of diverse chemical hazards, providing a powerful cleanup strategy for LC ...
Yanmin Liang, Hongyue Ma, Feier Bai, Jing Zhang, Yan Qi, Bing Shao   +5 more
wiley   +1 more source

Soil Fugitive Dust Pollution in Bole City Near Sayram Lake

GeoHealth
Soil fugitive dust significantly degrades air quality in arid regions like Bole City, China. To address methodological limitations causing Particulate matter (PM) overestimation, this study aimed to: (a) Develop a refined 2021 inventory for PM10 and PM2 ...
Yanyu Bai, Baoqing Wang, Ao Guo, Yuan Ji, Hasi Qingele, Yong Wang, Jieyu Wang, Jian Wang, Yan Jiang   +8 more
doaj   +1 more source

Membrane‐Active Peptide Protects Against Inflammation by Targeting NLRP3 Activation at the Trans‐Golgi Network

Advanced Science, EarlyView.
The membrane‐active peptide Pep19‐2.5 reduces harmful inflammation by blocking activation of the NLRP3 inflammasome at trans‐Golgi network membranes. By targeting key membrane interactions, Pep19‐2.5 suppresses inflammatory IL‐1β production and alleviates allergic airway inflammation in mice, leading to reduced immune cell infiltration and improved ...
Jonas Engelhardt, Nico Kirsch, Aileen Kerfin, Lars P. Lunding, Dominic Ferber, Hannes Buthmann, Ilka Schreier, Carlotta Bosio, Ann‐Kathrin Dobbelstein, Anna Klawonn, Rebecca C. Coll, Lena Bauernhofer, Sandro Keller, Matthias Geyer, Michael Wegmann, Andra B. Schromm, Günther Weindl   +16 more
wiley   +1 more source

Ecological effects of particulate matter

Environment International, 2003
Atmospheric particulate matter (PM) is a heterogeneous material. Though regulated as un-speciated mass, it exerts most effects on vegetation and ecosystems by virtue of the mass loading of its chemical constituents. As this varies temporally and spatially, prediction of regional impacts remains difficult.
D A, Grantz, J H B, Garner, D W, Johnson
openaire   +2 more sources