Comparisons of the effects of solute interactions on partition coefficient, kD, in selected binary immiscible solvents: a case of oxalic acid and succinic acid [version 1; peer review: 2 approved] [PDF]
F1000Research, 2022 Background: The molecular distributions of solutes in binary immiscible solvents as used in partition coefficient technique serve as measures of the solute separation, concentration and beneficiation from contaminants.
Chukwu P. I. +3 more
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Exploring the role of octanol-water partition coefficient and Henry’s law constant in predicting the lipid-water partition coefficients of organic chemicals [PDF]
Scientific Reports, 2022 Partition coefficients for storage lipid-water (logKlw) and phospholipid-water (logKpw) phases are key parameters to understand the bioaccumulation and toxicity of organic contaminants.
Muhammad Irfan Khawar +2 more
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Graph-based transformer to predict the octanol–water partition coefficient [PDF]
Journal of CheminformaticsLipophilicity is a fundamental physicochemical property that significantly influences various aspects of drug behavior, such as solubility, permeability, metabolism, distribution, protein binding, and excretion.
Vyacheslav Grigorev +4 more
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Improving the Hydrophilicity of the Drugs Paclitaxel, Violacein, and Tetrandrine Using Carbon-Based Quantum Dots [PDF]
NanomaterialsCarbon-based quantum dots and their nitrogen- and sulfur-doped derivatives were used as platforms to improve the aqueous solubility for Paclitaxel, Violacein and Tetrandrine, drugs with known high partition coefficients (Log P). Paclitaxel, Violacein and
Christine Wu +15 more
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Separation of Crocin/Betanin Using Aqueous Two-phase Systems Containing Ionic Liquid and Sorbitol [PDF]
Chemical and Biochemical Engineering Quarterly, 2022 Betanin and crocin, two food additives with attractive colors, are bioactive compounds of plants that are widely used in food, pharmaceutical, and medical industries. These bioactive pigments are sensitive to light, heat, organic solvents, and pH.
R. Madadi, S. Shahriari , H. Mozafari
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Octanol–Water Partition Coefficient Measurement by a Simple 1H NMR Method [PDF]
ACS Omega, 2017 Hemi Cumming, Christoph Rücker
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The effect of sulphates on partitioning of pectinases in aqueous two-phase systems [PDF]
Acta Periodica Technologica, 2004 The effect of various sulphate salts on the partitioning of endo-pectinase and exo-pectinase in aqueous two-phase systems, composed of polyethylene glycol and dextran, was studied.
Antov Mirjana G. +2 more
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Study on influencing factors of oil-water partition coefficient of phenolic compounds
Dizhi lixue xuebao, 2022 Alkylphenols are a kind of compounds produced by alkylation of phenolic compounds. Compared with other non-hydrocarbon compounds, alkylphenols are more soluble in water.
SUN Yanze +7 more
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Binding interactions of actinomycin D anticancer drug with bile salts micelles [PDF]
Journal of the Serbian Chemical Society, 2023 The interactions of actinomycin D (ActD) anticancer drug with two bile salts of different hydrophobicity (sodium cholate (NaC) and sodium deoxycolate (NaDC) and the influence of these bile salts aggregates on the ActD–DNA complex was investigated in 10 ...
Toader Ana Maria +3 more
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Solubility and Partition Coefficient of Salicylamide in Various pH Buffer Solutions
Indonesian Journal of Chemistry, 2021 The solubility and partition coefficient are essential physicochemical parameters in developing a pharmaceutical dosage form of medicine. In addition, these parameters help to predict the absorption of an active compound in oral or topical dosage forms ...
Dewi Isadiartuti +4 more
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