Results 101 to 110 of about 403,307 (296)
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Journal of Advanced Materials in Engineering, 2015 Certain amount of retained austenite can increase ductility of steels because of the TRIP phenomenon during plastic deformation. One method for achieving this is partitioning of carbon into austenite to stabilize it at room temperature. The quenching and
A. Shirali +2 more
doaj
Brazilian Archives of Biology and Technology, 2012 This work aimed to study the partitioning of a lipase produced by Burkholderia cepacia in PEG/Phosphate aqueous two phase system (ATPS) and its characterization. Lipase was produced by B. cepacia strains in a fermenter. Enzyme partitioning occurred at pH
Giovana da Silva Padilha +3 more
doaj +1 more source
Emerging experimental and computational methods for studying redox‐regulated structural transitions
FEBS Letters, EarlyView.Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding
FEBS Letters, EarlyView.In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança +2 more
wiley +1 more source
Simple K-Medoids Partitioning Algorithm for Mixed Variable Data
Algorithms, 2019 A simple and fast k-medoids algorithm that updates medoids by minimizing the total distance within clusters has been developed. Although it is simple and fast, as its name suggests, it nonetheless has neglected local optima and empty clusters that may ...
Weksi Budiaji, Friedrich Leisch
doaj +1 more source
FEBS Letters, EarlyView.Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav +2 more
wiley +1 more source
On Base Partitions and Cover Partitions of Skew Characters [PDF]
The Electronic Journal of Combinatorics, 2008 In this paper we give an easy combinatorial description for the base partition ${\cal B}$ of a skew character $[{\cal A}]$, which is the intersection of all partitions $\alpha$ whose corresponding character $[\alpha]$ appears in $[{\cal A}]$. This we use to construct the cover partition ${\cal C}$ for the ordinary outer product as well as for the ...
openaire +4 more sources
Polyhedral Computations for the Simple Graph Partitioning Problem [PDF]
The simple graph partitioning problem is to partition an edge-weighted graph into mutually disjoint subgraphs, each containing no more than b nodes, such that the sum of the weights of all edges in the subgraphs is maximal.
Sørensen, Michael M.
core
Tracking replicating HPV genomes in proliferating keratinocytes
mBioHuman papillomavirus (HPV) genomes replicate and partition as minichromosomes alongside host chromatin during persistent infection. However, it is difficult to monitor genome dynamics in living cells because the small and compact genome will not easily ...
Jonathan R. Shin +4 more
doaj +1 more source