Results 111 to 120 of about 1,911,864 (297)
COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells
Molecular Oncology, EarlyView.This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos +6 more
wiley +1 more source
Measuring correlation and entanglement between molecular orbitals on a trapped-ion quantum computer
Scientific ReportsQuantifying correlation and entanglement between molecular orbitals can elucidate the role of quantum effects in strongly correlated reaction processes.
Gabriel Greene-Diniz +6 more
doaj +1 more source
Microorganisms(1) Background: we determined the prevalence of the hepatitis B virus (HBV) amongst people without human immunodeficiency virus (HIV) in rural and peri-urban areas in Botswana.
Motswedi Anderson +18 more
doaj +1 more source
UCL (University College London) Libraries Masterplan: Masterplanning Report [PDF]
, 2008 BDP were appointed to undertake a Masterplan for the UCL Main Library and the UCL Science Library and to identify how these buildings could be re-ordered to significantly improve the quality of the library environment and to facilitate the delivery of
BDP (Building Design Partnership) +1 more
core
Molecular Oncology, EarlyView.Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
Developing an inter-university partnership: The importance of relationally-connected leaders [PDF]
, 2014 We have been involved in an inter-university partnership that supports, contributes to, and influences our own and others’ thinking and actions. As we have collaborated on teaching, learning, and research in the field of educational leadership, we ...
Ferrier-Kerr, Jenny L., Haxton, Paul
core +2 more sources
Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer
Molecular Oncology, EarlyView.COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann +61 more
wiley +1 more source
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Greening the Buffalo Niagara Medical Campus [PDF]
, 2015 The Medical Campus is dedicated to improving health, and a sustainable campus will improve the health of the patients, visitors, workers, and neighbors of the campus, as well as that of the general public. Sustainability measures such as improving energy
Partnership for the Public Good
core +1 more source
Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source