Results 91 to 100 of about 653,897 (318)

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Participatory Monitoring and Management Partnership

, 2015
The Participatory Monitoring and Management Partnership  (PMMP) is an international collaborative network for local leaders and communities working with participatory monitoring and management of natural resources. The Partnership seeks to transform
Participatory Monitoring and Management Partnership
core  

Partnership for Girls: Parent Focus Groups

, 2023
The Physical Activity Partnership for Girls was funded by the National Institute on Minority Health and Health Disparities (R24MD005096).This record contains materials for the focus groups conducted as part of the PA Partnership for Girls study.
Latino Research Institute, Deborah Parra-Medina, Ph.D., M.P.H.   +1 more
core   +1 more source

Perinatal depression among women in pregnancy and postpartum periods in Gaborone, Botswana

BMC Pregnancy and Childbirth
Introduction Perinatal depression is an important cause of maternal and infant morbidity. Rates of perinatal depression amongst pregnant and postpartum women in Botswana are not well-documented.
Rebecca Ryan, Aamirah Mussa, Chibuzor M. Babalola, Emily Hansman, Selebaleng Simon, Bame Bame, Neo Ndlovu, Lefhela Tamuthiba, Jeffrey D. Klausner, Chelsea Morroni, Adriane Wynn   +10 more
doaj   +1 more source

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

Molecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni, Antonella Palmese, Stefano Scalera, Laura Cipriani, Davide Mascolo, Patrizia Vici, Teresa Arcuri, Lorena Filomeno, Eriseld Krasniqi, Giovanni Blandino, Giulia Bon, Marcello Maugeri‐Saccà   +11 more
wiley   +1 more source

Connecticut Behavioral Health Partnership report to the legislature

, 2002
"The Departments of Children and Families (DCF), Mental Health and Addiction Services (DMHAS), and Social Services (DSS) have formed the Connecticut Behavioral Health Partnership ..."--P.
Connecticut Behavioral Health Partnership.
core  

Residencia Dunelm en la Universidad de Durham, Inglaterra

Informes de la Construccion, 1969
La configuración externa del edificio fue uno de los factores que de modo más acusado influyó en el diseño de la «Dunelm House», cuyo mayor atractivo quizás sea su expresión formal escultórica.
Arquitectos Co. Partnership, Partners Ove Arup   +1 more
doaj   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source

Corporate responsibility, supply chain partnership and performance: An empirical examination

, 2012
This is the post-print version of the final paper published in International Journal of Production Economics. The published article is available from the link below. Changes resulting from the publishing process, such as peer review, editing, corrections,
Ghobadian, A, Ghobadian, A., Gallear, D, Chen, Weifeng, Gallear, David, Chen, W., Weifeng Chen, David Gallear, Abby Ghobadian, Chen, W, Ghobadian, Abby, Gallear, D.   +11 more
core   +1 more source