Results 111 to 120 of about 653,897 (318)
Molecular Oncology, EarlyView.Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen +14 more
wiley +1 more source
, 2003 The programme is designed to be an alternative model of development assistance, operating regionally, nationally, and locally and dedicated to building local institutional effectiveness in Sub-Saharan Africa.
Municipal Development Partnership
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Molecular Oncology, EarlyView.Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source
Measuring correlation and entanglement between molecular orbitals on a trapped-ion quantum computer
Scientific ReportsQuantifying correlation and entanglement between molecular orbitals can elucidate the role of quantum effects in strongly correlated reaction processes.
Gabriel Greene-Diniz +6 more
doaj +1 more source
Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
Molecular Oncology, EarlyView.IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source
National Partnership for Reinventing Government
, 1998 The National Partnership for Reinventing Government (NPR), originally the National Performance Review, was the Clinton-Gore Administration's interagency task force to reform and streamline the way the federal government works. It was the eleventh federal
National Partnership for Reinventing Government
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Microorganisms(1) Background: we determined the prevalence of the hepatitis B virus (HBV) amongst people without human immunodeficiency virus (HIV) in rural and peri-urban areas in Botswana.
Motswedi Anderson +18 more
doaj +1 more source
Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
Molecular Oncology, EarlyView.In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source
Annual report to the Behavioral Health Partnership Oversight Council. 2010: Dec.
, 2012 Annual; Began with 2009?; "Pursuant to CGS Section 17a-22m ..."--Letter of transmittal (publisher's Web site, viewed Apr. 1, 2011)
Connecticut Behavioral Health Partnership.
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Molecular Oncology, EarlyView.Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller +10 more
wiley +1 more source