Results 81 to 90 of about 1,924,515 (315)

Two steps forward, one step back: Achievements and limitations of university-community partnerships in addressing neighbourhood socioeconomic disadvantage [PDF]

, 2016
This article discusses a partnership initiative that involved a major Australian research university (University of Melbourne), a local government and a network of local community service organisations.
Warr, Deborah, Williams, Richard
core   +3 more sources

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

Malaria case investigation with reactive focal testing and treatment: operational feasibility and lessons learned from low and moderate transmission areas in Amhara Region, Ethiopia

Malaria Journal, 2018
Background When malaria transmission is very low, investigation of passively detected malaria cases and reactive focal testing and treatment (FTAT) in the case and neighbouring households can identify and contain the source and spread of infections ...
Pooja Bansil, Asnakew K. Yeshiwondim, Caterina Guinovart, Belendia Serda, Callie Scott, Berhane H. Tesfay, Adem Agmas, Belay Bezabih, Melkamu T. Zeleke, Girma S. Guesses, Asmamaw L. Ayenew, Worku M. Workie, Duncan Earle, Rick W. Steketee, Asefaw Getachew   +14 more
doaj   +1 more source

The Partnership Bill 2003: unnecessary tinkering or much-needed reform? [PDF]

, 2005
Purpose - To examine the nature and merits of the proposed changes to partnership law contained in the draft Partnership Bill published in the Law Commission's Partnership Law Report (2003).
Berry, E
core  

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

Molecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff, Manuela Moritz, Dennis Eggert, Anna Worthmann, Joerg Heeren, Henrike Zech, Till S. Clauditz, Waldemar Wilczak, Hartmut Schlüter, Christian S. Betz, Arne Böttcher, Jan Hahn   +11 more
wiley   +1 more source

A Federated Data Linkage Strategy to Support Population Health Research in Canada

International Journal of Population Data Science, 2017
Objectives Canada has established a pan-Canadian cohort with over 300,000 volunteer participants aged 35-69, to support research on cancer and chronic disease. A key feature of the cohort is that participants have consented to link their cohort data with
Tanya Flanagan, Céline Moore, Carolyn Sandoval   +2 more
doaj   +1 more source

Partnership in practice [PDF]

, 2002
This paper examines human resource management practices adopted in a group of eight case study firms and their tendencies towards versus away from partnership.
Hudson, M., Konzelmann, Suzanne J., Wilkinson, F.   +2 more
core  

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

Molecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala, Sini Ahonen, Sara Peltola, Aura Tuohisto‐Kokko, Olaya Esparta, Peppi Suominen, Anne Jokilammi, Iman Farahani, Deepankar Chakroborty, Nikol Dibus, Steffen Boettcher, Tomi T. Airenne, Mark S. Johnson, Lisa D. Eli, Klaus Elenius, Kari J. Kurppa   +15 more
wiley   +1 more source

Perinatal depression among women in pregnancy and postpartum periods in Gaborone, Botswana

BMC Pregnancy and Childbirth
Introduction Perinatal depression is an important cause of maternal and infant morbidity. Rates of perinatal depression amongst pregnant and postpartum women in Botswana are not well-documented.
Rebecca Ryan, Aamirah Mussa, Chibuzor M. Babalola, Emily Hansman, Selebaleng Simon, Bame Bame, Neo Ndlovu, Lefhela Tamuthiba, Jeffrey D. Klausner, Chelsea Morroni, Adriane Wynn   +10 more
doaj   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source