Results 61 to 70 of about 1,543,646 (293)

Business Models for Sustainable Finance: The Case Study of Social Impact Bonds [PDF]

open access: yes, 2019
Business models for sustainability (BMfS) are relevant topics on research agendas, given their orientation toward sustainability issues. However, traditional versions of these models are often ill-equipped at solving complex social problems. Cross-sector
Chiappini, Helen   +3 more
core   +1 more source

Integration of circadian and hypoxia signaling via non‐canonical heterodimerization

open access: yesFEBS Letters, EarlyView.
CLOCK, BMAL1, and HIFs are basic helix‐loop‐helix and Per‐Arnt‐Sim domain (bHLH‐PAS) proteins, which function as transcription factors. bHLH‐PAS proteins are designated in two classes. Many class I proteins are regulated by environmental signals via their PAS domains, but such signals have not been identified for all.
Sicong Wang, Katja A. Lamia
wiley   +1 more source

Partnership Research: A Pathway to Realize Multistakeholder Participation [PDF]

open access: yesInternational Journal of Qualitative Methods, 2019
Partnership research projects between academic researchers, service providers, policy makers, and persons from vulnerable populations are increasingly promoted as a means to inform and improve research and practice. Key elements in partnership research are the participation of multiple stakeholders and a shared responsibility and control over ideas ...
Numans, Wilma   +2 more
openaire   +4 more sources

Perceptions and determinants of partnership trust in the context of Community-Based Participatory Research [PDF]

open access: yes, 2020
Trust is difficult to conceptualize and define because of its diverse applications in different disciplines. Historic mistrust between vulnerable communities and researchers based on past adverse experiences can negatively affect the ability to ...
Moore de Peralta, Arelis   +2 more
core   +2 more sources

Function‐driven design of a surrogate interleukin‐2 receptor ligand

open access: yesFEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang   +9 more
wiley   +1 more source

Partnership in research [PDF]

open access: yesCanadian Journal of Occupational Therapy, 2016
Background. Partnerships in occupational therapy between practitioners and researchers are important to advance knowledge relevant to clinical practice and support evidence-based practice in the profession. Purpose.
openaire   +1 more source

Your money matters evaluation: money management for older people [PDF]

open access: yes, 2009
The National Research and Development Centre for adult literacy and numeracy (NRDC) was commissioned by Help the Aged to evaluate Your Money Matters, a free, confidential and impartial money advice service for older people run by Help the Aged in ...
Brazier, Laura   +3 more
core  

The newfound relationship between extrachromosomal DNAs and excised signal circles

open access: yesFEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Building bridges: enhancing cultural understanding and community engagement in the CHAMPS program—experience sought from Gobe Challa Village, Ethiopia

open access: yesDiscover Social Science and Health
Public health programs’ successful implementation often requires a thorough consideration ⁠ of local cultural contexts and effective community engagement.
Haleluya Leulseged   +20 more
doaj   +1 more source

An International Cross-cohort Harmonization and Data Integration Initiative towards Achieving Statistical Power and Meaningful Results

open access: yesInternational Journal of Population Data Science, 2017
Objectives The complex interaction between lifestyle, behaviours, genetic factors and the social and physical environment have a fundamental role in modulating risk and/ or progression of health outcomes, especially cancer.
Tanya Flanagan   +3 more
doaj   +1 more source

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