Results 81 to 90 of about 416,239 (311)

The discrepancy of antemortem clinical diagnosis and postmortem autopsy diagnosis of lung pathologies in under-five deaths and the reasons for discrepancies: a case series analysis

BMC Pediatrics
Background Diagnostic autopsy is the most reliable approach to definitively ascertain the cause of death and evaluate the accuracy of antemortem clinical diagnoses.
Haleluya Leulseged, Chris A. Rees, Addisu Alemu, Beth A. Tippett Barr, Merga Dheresa, Lola Madrid, Anthony Scott, Nega Assefa   +7 more
doaj   +1 more source

Hepatitis Delta Virus Clade 8 Is the Predominant Clade Circulating in Botswana amongst People Living with HIV

Viruses
Hepatitis delta virus (HDV) co-infections more often result in severe hepatitis compared to hepatitis B virus (HBV) infections alone. Despite a high HDV prevalence (7.1%), information regarding circulating HDV clades is very limited in Botswana.
Kabo Baruti, Wonderful T. Choga, Patience C. Motshosi, Bonolo B. Phinius, Basetsana Phakedi, Lynnette N. Bhebhe, Gorata G. A. Mpebe, Chanana D. Tsayang, Tsholofelo Ratsoma, Tendani Gaolathe, Mosepele Mosepele, Joseph Makhema, Roger Shapiro, Shahin Lockman, Sikhulile Moyo, Mosimanegape Jongman, Motswedi Anderson, Simani Gaseitsiwe   +17 more
doaj   +1 more source

Research Partnerships and Collaboration in Cardiovascular Nursing [PDF]

European Journal of Cardiovascular Nursing, 2004
Whilst cardiovascular nursing has undergone significant change and has developed considerably in recent years, cardiovascular nurses still tend to work in comparative isolation from one another, whether it is in terms of practice, education, or research.
openaire   +4 more sources

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

Gamification & Research – Partnership for Innovation

Procedia Economics and Finance, 2015
AbstractResearch is the source of innovation. Research in any field requires creativity and motivation for innovative ideas to emerge. This paper aims to present elements of gamification used in a research project on 3D virtual environments. In this context we identify the components of the innovative partnership gamification and research, namely, how ...
Ionica, Andreea Cristina, Leba, Monica
openaire   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

Stereotactic ablative radiotherapy-driven immunosuppression is associated with poorer progression-free survival in cancer patients

Cancer Immunology, Immunotherapy
Background The landscape of cancer treatment has evolved rapidly within the last 50 years, and whilst radiotherapy, chemotherapy, and surgery remain the mainstay treatment options, there has been a shift towards using immunotherapy alone or in ...
Jessica Oliver, Hannah Reed, Lorenzo Capitani, Ashley Poon-King, Ashleigh Young, Stefan Milutinovic, Mateusz Kuczynski, Owen Nicholas, Thomas Rackley, Catherine Pembroke, Andrew Godkin, Awen M. Gallimore   +11 more
doaj   +1 more source

Strengthening Healthcare through Academic and Industry Partnership Research. [PDF]

Nepal J Epidemiol, 2023
Sathian B, van Teijlingen E, Simkhada P, Banerjee I, Manikyam HK, Kabir R.   +5 more
europepmc   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

Molecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau, Leonor Garcia, Hugo Arnold, Antonija Hanžek, Maialen Arrieta, Laurent R Gauthier, Christine Granotier‐Beckers, François D Boussin, Amaury Herbet, Marie Hautière, Valentin Asei‐Ceschino, Clémentin Jacques, Laura Brard, Thomas Harnois, Valérie Coronas, Bruno Constantin, Aurélien Chatelier, Jean Chemin, Serge Urbach, Martial Seveno, Szimonetta Hideg, Chantal Ripoll, Kasandra Aguilar‐Cázarez, Min Zheng, Guo‐Hao Huang, Sheng‐Qing Lv, Lei Zhang, Philippe Rondard, Laurent Prezeau, Jean‐Philippe Pin, Hugues Duffau, Luc Bauchet, Valérie Rigau, Franck Denat, Charles Truillet, Didier Boquet, Jean‐Philippe Hugnot   +36 more
wiley   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source