Molecular Oncology, EarlyView.AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou +5 more
wiley +1 more source
Cancer Immunology, ImmunotherapyBackground The landscape of cancer treatment has evolved rapidly within the last 50 years, and whilst radiotherapy, chemotherapy, and surgery remain the mainstay treatment options, there has been a shift towards using immunotherapy alone or in ...
Jessica Oliver +11 more
doaj +1 more source
Strengthening Healthcare through Academic and Industry Partnership Research. [PDF]
Nepal J Epidemiol, 2023 Sathian B +5 more
europepmc +1 more source
Shaping Global Partnerships for a Post-2015 World [PDF]
, 2014 As we discuss the post-2015 development agenda, how can we empower global partnerships to achieve the transformational change we need for a better future?
Angela Barmettler +4 more
core
Synthetic chemistry and biological activity of pentafluorosulphanyl (SF5) organic molecules [PDF]
, 2012 Acknowledgements We thank the European Commission for financial support (Industry Academia Partnerships and Pathways project “PET BRAIN”, Contract No 251482). S.A.
Altomonte, Stefano, Zanda, Matteo
core +1 more source
Molecular Oncology, EarlyView.This study indicates that Merkel cell carcinoma (MCC) does not originate from Merkel cells, and identifies gene, protein & cellular expression of immune‐linked and neuroendocrine markers in primary and metastatic Merkel cell carcinoma (MCC) tumor samples, linked to Merkel cell polyomavirus (MCPyV) status, with enrichment of B‐cell and other immune cell
Richie Jeremian +10 more
wiley +1 more source
Public-private partnerships in agricultural research: an analysis of challenges facing industry and the Consultative Group on International Agricultural Research [PDF]
"Public-private partnerships offer potentially important opportunities for pro-poor agricultural research in developing countries. Yet in the international agricultural research community-and with regard to the Consultative Group on International ...
Spielman, David J., von Grebmer, Klaus
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The University of New Hampshire Engaged Scholars Academy: Instilling in Faculty Principles of Effective Partnership [PDF]
, 2013 Over the last decade, the University of New Hampshire (UNH) has promoted mutually beneficial partnerships between faculty and community partners vis-à-vis the Engaged Scholars Academy (ESA), a faculty development program aimed at enhancing faculty ...
Abrams, Eleanor +7 more
core +1 more source
YAP1::TFE3 mediates endothelial‐to‐mesenchymal plasticity in epithelioid hemangioendothelioma
Molecular Oncology, EarlyView.The YAP1::TFE3 fusion protein drives endothelial‐to‐mesenchymal transition (EndMT) plasticity, resulting in the loss of endothelial characteristics and gain of mesenchymal‐like properties, including resistance to anoikis, increased migratory capacity, and loss of contact growth inhibition in endothelial cells.
Ant Murphy +9 more
wiley +1 more source
Advancing Health Services Collaborative and Partnership Research Comment on "Experience of Health Leadership in Partnering with University-Based Researchers in Canada - A Call to 'Re-imagine' Research". [PDF]
Int J Health Policy Manag, 2021 Nyström ME, Strehlenert H.
europepmc +1 more source