Results 171 to 180 of about 133,619 (388)
Emerging Therapeutic Strategies for Hearing Loss
Challenges still exist in treating hearing loss in cases of severe damage to hair cells or spiral ganglion neurons. Here, a schematic diagram of cochlear sensory hair cells and auditory nerves is presented. It is found that in normal Corti organs, hair cells have upright stereocilia at the top and auditory neurons at the base. Ototoxic drugs, noise, or
Shanying Han+9 more
wiley +1 more source
The present study constructs machine‐learning models to resolve developmental relationships among auditory performance, auditory cortical processing, and functional connectivity of the bilateral language network during the first year of restored hearing. The results demonstrate that asymmetric inter‐hemisphere communication contributes significantly to
Xue Zhao+6 more
wiley +1 more source
Worldwide, there is a trend towards increased herd sizes, and the animal-to-stockman ratio is increasing within the beef and dairy sectors; thus, the time available to monitoring individual animals is reducing. The behaviour of cows is known to change in
G.A. Miller+10 more
doaj
D2HGDH Deficiency Regulates Seizures through GSH/Prdx6/ROS‐Mediated Excitatory Synaptic Activity
Downregulating D‐2‐hydroxyglutarate dehydrogenase (D2HGDH) increases epilepsy susceptibility by altering reactive oxygen species (ROS) levels and synaptic function, contributing to oxidative stress in neurons. The acid calcium‐independent phospholipase A2 (aiPLA2) inhibitor MJ33 restores glutathione reduced/glutathione oxidized balance, reducing ROS ...
Zhijuan Zhang+14 more
wiley +1 more source
Variations in serum-magnesium and in the partition of serum-calcium in normal parturition and in milk fever [PDF]
W. Godden, J. Duckworth
openalex +1 more source
The Placenta Regulates Intrauterine Fetal Growth via Exosomal PPARγ
The placenta expresses much higher levels of PPARγ than fetal adipose tissue. Trophoblastic exosomes transport PPARγ into fetal preadipocytes via fetoplacental circulation and thus regulate adipogenic genes distinct from endogenous PPARγ. Compromised placental PPARγ leads to fetal adipogenesis deficiency and intrauterine growth restriction, reversible ...
Xiaofang Luo+17 more
wiley +1 more source
Pelvic organ prolapse (POP) is a significant health challenge for women, especially with the lack of optimal surgical options post‐withdrawal of synthetic transvaginal meshes. The study pioneers degradable melt electrowrite vaginal implants with precise 22.5° angles and specific porosity. These configurations significantly influence macrophage behavior
Kallyanashis Paul+7 more
wiley +1 more source
Modeling hormonal and inflammatory contributions to preterm and term labor using uterine temporal transcriptomics [PDF]
Bennett, PR+9 more
core +1 more source