Results 171 to 180 of about 109,019 (287)

Mitochondrial dysfunction in the bovine mammary gland: regulatory mechanisms and therapeutic strategies. [PDF]

J Anim Sci Biotechnol
Shen T, Li M, Sun X, Deng Z, Pitts H, Nolan D, Loor JJ, Xu C.   +7 more
europepmc   +1 more source

Phosphatidic Acid‐TRIM59‐Olig2 Signaling Couples Metabolic Dysfunction to Myelination Failure in PWMI

Advanced Science, EarlyView.
PA accumulates after hypoxic‐ischemic injury and stabilizes the E3 ligase TRIM59 in OPCs. Stabilized TRIM59 enhances ubiquitination and degradation of Olig2, blocking differentiation and causing hypomyelination in PWMI. Modulating PA synthesis restores Olig2 levels, improves myelination, and ameliorates behavioral deficits, defining a metabolically ...
Xinyu Li, Yanan Liu, Meng Zhang, Yiwei Liu, Meiting Liu, Kaishen Zhu, Zhian Liu, Chao Ren, Ruiqin Yao   +8 more
wiley   +1 more source

Effects of dietary supplementation of pioglitazone on metabolism, milk yield and reproductive performance in transition dairy cows [PDF]

Fouladi-Nashta, A A, Kohram, H, Shahneh, A Z, Yousefi, A R, Zamiri, M J   +4 more
core   +1 more source

Adult Sex Ratio as a Demographic Feedback Linking Mating Systems, Parental Care, and Evolution

Advanced Science, EarlyView.
Breeding systems are some of the most diverse social behavior, and our team is investigation the evolutionary causes of this diversity. This review summarises our research carried out at the University of Bath. We argue that demographic components of wild populations, especially the adult sex ratio, plays a key role driving breeding system variation ...
Tamás Székely, Oscar G. Miranda
wiley   +1 more source

An Energetic Tradeoff Best Explains Parturition Timing in Grizzly Bears. [PDF]

Ecol Evol
Costello CM, Roberts LL, Bjornlie DD, Cameron MD, Clapp JG, Haroldson MA, Hilderbrand GV, Joly K, Kasworm WF, Nicholson JM, Radandt TG, Sorum MS, Teisberg JE, van Manen FT, Vinks MA.   +14 more
europepmc   +1 more source

Large Room Temperature Anomalous Nernst Effect Coupled with Topological Nernst Effect from Incommensurate Spin Structure in a Kagome Antiferromagnet

Advanced Science, EarlyView.
This study demonstrates that ErMn₆Sn₆, a kagome antiferromagnet hosting incommensurate spin textures, sustains finite scalar spin chirality that drives topological states. The anomalous Nernst effect (ANE) originates from the strong Berry curvature of Chern‐gapped Dirac fermions, while the topological Nernst effect (TNE) arises from emergent fields ...
Jiajun Ma, Jiaxing Liao, Yazhou Li, Yuwei Zhang, Jialu Wang, Jinke Bao, Yan Sun, Shuang Jia, Yuke Li   +8 more
wiley   +1 more source

Expression of free fatty acid receptors in the liver of periparturient dairy cows supplemented with essential fatty acids and conjugated linoleic acid. [PDF]

JDS Commun
Michelotti TC, Imbert A, Veshkini A, Durand G, Hammon HM, Bonnet M.   +5 more
europepmc   +1 more source

Cars2‐Mediated Cysteine Catabolism Drives Brown Fat Development and Thermogenesis Through Persulfidating EBF2

Advanced Science, EarlyView.
We demonstrate that Cars2, a cysteine catabolic enzyme in mouse iBAT, is critical for cold tolerance and brown adipocyte differentiation. Through its CPERS activity, Cars2 produces CysSSH/H2S to induce EBF2 persulfidation, promoting its interaction with PPARγ and BRG1 to enhance thermogenic gene expression.
Xin Peng, Hongyong Song, Yin Long, Kaimin Wu, Yinkun Fu, Wenkai Zhou, Wenyan Li, Zhe Shi, Xu‐Yun Zhao   +8 more
wiley   +1 more source

Periparturient alpha-lipoic acid supplementation improves ewe antioxidant status, colostrum quality, and lamb growth. [PDF]

Trop Anim Health Prod
Eldawy MH, Elken EM, Elnady IA, Asfour HAE, Mehany EN, Rashad MG, Samir H, El-Sherbiny HR, Fahim NH.   +8 more
europepmc   +1 more source

Deciphering the Evolution Pattern of Structural Variations Overlapped With Repetitive Sequence During Cattle Evolution

Advanced Science, EarlyView.
The authors complement bovine pan‐SV with massive novel structural variations (SVs) identified through long‐read sequencing of 83 globally distributed cattle breeds. Repetitive sequence‐mediated SVs (rep‐SV) exhibit distinct dynamic patterns throughout cattle sub‐speciation and/or domestication processes, including uneven distribution between chr‐X and
Zhifan Guo, Jinxiu Li, Adeniyi C. Adeola, Xueyan Jiang, Juntao Ma, Jian Xiao, Dexiang Hu, Kaixing Qu, Haihong Wu, Junren Chen, Zhanxing He, Tingting Yin, Ali Esmailizadeh, Jing Luo, Olivier Hanotte, Ya‐Ping Zhang, Yan Li   +16 more
wiley   +1 more source