Results 131 to 140 of about 677,401 (344)

Gravity sensing, a largely misunderstood trigger of plant orientated growth

open access: yesFrontiers in Plant Science, 2014
Gravity is a crucial environmental factor regulating plant growth and development. Plants have the ability to sense a change in the direction of gravity, which leads to the re-orientation of their growth direction, so-called gravitropism.
David eLopez   +9 more
doaj   +1 more source

Comparative cranial biomechanics reveal macroevolutionary trends in theropod dinosaurs, with emphasis on Tyrannosauroidea

open access: yesThe Anatomical Record, EarlyView.
Abstract Tyrannosaurus is viewed as a model organism in vertebrate paleontology, with numerous studies analyzing its feeding biomechanics. Nonetheless, the evolution of this feeding performance has been under‐addressed in Tyrannosauroidea, especially in basal tyrannosauroids. Here we used muscle‐force reconstruction and finite element analysis (FEA) to
Evan Johnson‐Ransom   +4 more
wiley   +1 more source

Data with hierarchical structure: impact of intraclass correlation and sample size on Type-I error

open access: yesFrontiers in Psychology, 2011
Least squares analyses (e.g., ANOVAs, linear regressions) of hierarchical data leads to Type-I error rates that depart severely from the nominal Type-I error rate assumed. Thus, when least squares methods are used to analyze hierarchical data coming from
Serban C Musca   +6 more
doaj   +1 more source

Mission de M. Pascal Lanco en Angleterre [PDF]

open access: yes, 1908
Lanco Pascal. Mission de M. Pascal Lanco en Angleterre. In: École pratique des hautes études, Section des sciences historiques et philologiques. Annuaire 1909-1910. 1909. pp.
Lanco, Pascal
core  

Pharmacokinetics, effectiveness and safety of certolizumab pegol in children and adolescents with active juvenile idiopathic arthritis: 9+‐year results from a multicenter, open‐label study

open access: yesArthritis &Rheumatology, Accepted Article.
Objective To assess the pharmacokinetics, effectiveness, safety, and immunogenicity of certolizumab pegol (CZP) in polyarticular‐course juvenile idiopathic arthritis (pcJIA). Methods Pediatric Arthritis Study of Certolizumab Pegol (NCT01550003), a multicenter, open‐label study, enrolled patients 2–17 years with active pcJIA and inadequate response ...
Hermine I Brunner   +28 more
wiley   +1 more source

Repeated intradermal lipopolysaccharide challenge responses in healthy volunteers: Implications for clinical pharmacology studies

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Aim Intradermal application of lipopolysaccharide (LPS), a Toll‐like receptor 4 agonist, induces a local inflammatory response and is used as a human challenge model to evaluate the pharmacodynamics of investigational medicinal products. While currently applied in a single, parallel‐group setting, alternative within‐subject designs involving repeated ...
Alexandra A. J. Sillé   +12 more
wiley   +1 more source

Infusion rate adjustment in enzyme replacement therapy with pabinafusp alfa for mucopolysaccharidosis II

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Abstract Aims Enzyme replacement therapy (ERT) for mucopolysaccharidosis II (MPS II) requires long‐term, weekly intravenous infusions often lasting over 3 h each time, which can burden paediatric patients and caregivers and negatively affect their quality of life and treatment compliance.
Kimitoshi Nakamura   +6 more
wiley   +1 more source

The perception of Blaise Pascal and his legacy by the official Soviet culture of the 1920–1930s [PDF]

open access: yesИзвестия Саратовского университета. Новая серия: Серия Филология, Журналистика
The perception of Blaise Pascal by the official Soviet culture of the 1920–1930s has not yet become the subject of a special study. At a new historical turn, the scientific and spiritual legacy of the French thinker was inevitably subject to ...
Kashlyavik, Kira Urievna   +1 more
doaj   +1 more source

Conceptualizing Corporate Political Activity for Sustainability Governance—The CPA Cube

open access: yesBusiness Strategy and the Environment, EarlyView.
ABSTRACT Sustainability transformations in the economy, and related public policy decisions, are highly contested, attracting business involvement. To better understand how business influence on government impacts the success or failure of sustainability governance efforts, this paper extends the literature on corporate political activity (CPA) by ...
Burkard Eberlein, Janina Grabs
wiley   +1 more source

Safety and efficacy of panretinal photocoagulation in patients with high-risk proliferative diabetic retinopathy using pattern scan laser versus conventional YAG laser

open access: yesKaohsiung Journal of Medical Sciences, 2016
The purpose of the study was to compare the results of panretinal photocoagulation (PRP) using the pattern scan laser (PASCAL) in a single setting versus multiple sessions of standard YAG laser in patients with proliferative diabetic retinopathy.
Recep Göktuğ Seymenoğlu   +2 more
doaj   +1 more source

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