Results 111 to 120 of about 1,271,785 (295)

Assisted finite-rate adiabatic passage across a quantum critical point: Exact solution for the quantum Ising model

, 2012
The dynamics of a quantum phase transition is inextricably woven with the formation of excitations, as a result of the critical slowing down in the neighborhood of the critical point.
Adolfo del Campo, Marek M. Rams, S. Sachdev, V. Gritsev, W. H. Zurek, Wojciech H. Zurek   +5 more
core   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

First-passage problems: A probabilistic dynamic analysis for degraded structures [PDF]

Structures subjected to random excitations with uncertain system parameters degraded by surrounding environments (a random time history) are studied. Methods are developed to determine the statistics of dynamic responses, such as the time-varying mean ...
Chamis, Christos C., Shiao, Michael C.
core   +1 more source

Quenched large deviations for multidimensional random walk in random environment with holding times

, 2013
We consider a random walk in random environment with random holding times, that is, the random walk jumping to one of its nearest neighbors with some transition probability after a random holding time.
A Dembo, A Yilmaz, AS Sznitman, E Kosygina, E Kosygina, F Rassoul-Agha, JT Cox, M Flury, MPW Zerner, Naoki Kubota, Ryoki Fukushima   +10 more
core   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source

Temporal Passage and the 'no alternate possibilities' argument

Manuscrito
Dynamic theories of time typically commit to the claim that "time passes". In this paper I develop a version of the 'no alternate possibilities' argument in order to show that time does not pass, but that this is no threat to dynamic theories of time.
Jonathan Tallant
doaj   +1 more source

The process of irreversible nucleation in multilayer growth. II. Exact results in one and two dimensions

, 2002
We study irreversible dimer nucleation on top of terraces during epitaxial growth in one and two dimensions, for all values of the step-edge barrier. The problem is solved exactly by transforming it into a first passage problem for a random walker in a ...
C. Castellano, C. Ratsch, Claudio Castellano, G. Ehrlich, I. Elkinani, J. Krug, J. Krug, J. Tersoff, J.A. Venables, J.A. Venables, K. Kyuno, M.E. Fisher, P. Politi, P. Politi, Paolo Politi, R.L. Schwoebel, R.L. Schwoebel, S. Heinrichs   +17 more
core   +1 more source

Marking Food for Studying Its Rate of Passage in Poultry

Poultry Science, 1965
Abstract A review of methods used to study the rate of food passage in poultry shows that no consistant technique for marking food has been adopted. Apparently no indicator possessing all the necessary requirements of a reliable marker has been found and described. An effective marker must have the following qualities. It must be convenient and easy
openaire   +2 more sources

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon, Peter T. Gallagher, Orly I. Richter, Neermala Poudel Neupane, Amy C. Mandigo, Jennifer J. McCann, Emanuela Dylgjeri, Irina Vasilevskaya, Christopher McNair, Channing J. Paller, Wm. Kevin Kelly, Karen E. Knudsen, Matthew J. Schiewer, Ayesha A. Shafi   +13 more
wiley   +1 more source

Contributions of differential p53 expression in the spontaneous immortalization of a chicken embryo fibroblast cell line

BMC Cell Biology, 2006
Background The present study was carried out to determine whether the p53 pathway played a role in the spontaneous immortalization of the SC-2 chicken embryo fibroblast (CEF) cell line that has been in continuous culture for over three years. Results The
Kim Hyunggee, Landry Megan M, Kong Byung-Whi, Christman Shelly A, Foster Douglas N   +4 more
doaj   +1 more source