Results 101 to 110 of about 5,794,714 (263)
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
FEBS Letters, EarlyView.The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
FEBS Letters, EarlyView.GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source
An Analysis of a Child Called ‘It’ by Dave Pelzer from Family Systems Theory Perspective [PDF]
, 2019 Child abuse has a major and long lasting effect on children’s lives. Besides leaving horrible memories, the child abuse also affects the relationships among family members. This paper analyses a novel which consists of child abuse entitled A Child Called
Fitriyantisyam, Hafizha
core +1 more source
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
A Comparative Analysis of Unedited and Published Translation Works in The Pikiran Rakyat Newspaper
, 2019 This descriptive qualitative study aims at discovering types of translation strategies and changes which occur in a student’s translation works. The data were obtained from a student’s 10 unedited translation works from English to Bahasa Indonesia and 10
Mawarni, Wiwit Sekar
core +1 more source
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
FEBS Letters, EarlyView.Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
, 2019 This qualitative descriptive study aims to analyze the equivalence technique in English-Bahasa Indonesia translation of slang and swear words in Deadpool movie. The concept of formal and dynamic equivalences which is proposed by Nida (1964) is applied in
Karinda, Ajeng Mediastri
core +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Temporal Passage and the 'no alternate possibilities' argument
ManuscritoDynamic theories of time typically commit to the claim that "time passes". In this paper I develop a version of the 'no alternate possibilities' argument in order to show that time does not pass, but that this is no threat to dynamic theories of time.
Jonathan Tallant
doaj +1 more source