Results 91 to 100 of about 1,271,785 (295)

Film-cooling effectiveness with developing coolant flow through straight and curved tubular passages [PDF]

The data were obtained with an apparatus designed to determine the influence of tubular coolant passage curvature on film-cooling performance while simulating the developing flow entrance conditions more representative of cooled turbine blade.
Graham, R. W., Papell, S. S., Wang, C. R.   +2 more
core   +1 more source

The X-ray Ridge Surrounding Sgr A* at the Galactic Center

, 2005
We present the first detailed simulation of the interaction between the supernova explosion that produced Sgr A East and the wind-swept inner ~ 2-pc region at the Galactic center.
Christopher L. Fryer, Cuadra J., Frederick K. Baganoff, Fulvio Melia, Gabriel Rockefeller, Mezger P. G., Monaghan J. J.   +6 more
core   +1 more source

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source

Stress and strain among merchant seafarers differs across the three voyage episodes of port stay, river passage and sea passage.

PLoS ONE, 2019
BackgroundA sea voyage is characterized by a variety of work requirements for the ship's crew, basically reflected in three voyage episodes: port stay, river passage and sea passage.
Marcus Oldenburg, Hans-Joachim Jensen
doaj   +1 more source

On Short-Term Loan Interest Rate Models: A First Passage Time Approach

Mathematics, 2018
In this paper, we consider a stochastic diffusion process able to model the interest rate evolving with respect to time and propose a first passage time (FPT) approach through a boundary, defined as the “alert threshold”, in order to evaluate
Giuseppina Albano, Virginia Giorno
doaj   +1 more source

Enhancement of stability in randomly switching potential with metastable state

, 2004
The overdamped motion of a Brownian particle in randomly switching piece-wise metastable linear potential shows noise enhanced stability (NES): the noise stabilizes the metastable system and the system remains in this state for a longer time than in the ...
A. A. Dubkov, Agudov, Agudov, Apostolico, B. Spagnolo, Balakrishnan, Chong-Wei, Dan, Dayan, Doering, Doering, Dubkov, Fiasconaro, Furutsu, Hirsch, Lehmann, Mahato, Mahato, Maier, Malakhov, Mantegna, Mantegna, Mantegna, Marchi, Masoliver, Matsumoto, Mielke, N. V. Agudov, Novikov, Reimann, Rodrigues, Shapiro, Smelyanskiy, Spagnolo, Wackerbauer, Wackerbauer, Yoshimoto, Zürcher, Łuczka   +38 more
core   +2 more sources

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

Strain-to-strain variation of Rhodococcus equi growth and biofilm formation in vitro

BMC Research Notes, 2019
Objective Rhodococcus equi is an opportunistic pathogen that causes disease worldwide in young foals and immunocompromised humans. The interactions of R.
Adina R. Bujold, Nicholas R. Lani, Macarena G. Sanz   +2 more
doaj   +1 more source

Knotting probabilities after a local strand passage in unknotted self-avoiding polygons

, 2011
We investigate the knotting probability after a local strand passage is performed in an unknotted self-avoiding polygon on the simple cubic lattice.
Bates A, Berg B, Berger J M, Berretti A, Buck G, Burnier Y, C E Soteros, Clisby N, de Carvalho C A, de Carvalho C A, Fishman G S, Fogg J M, Gelman A, Gelman A, Guttmann A J, Hua X, Janse van Rensburg E J, Janse van Rensburg E J, Janse van Rensburg E J, Janse van Rensburg E J, Liu Z, Liu Z, Liu Z, Liu Z R, M L Szafron, Manturov V, Marcone B, Orlandini E, Orlandini E, Orlandini E, Rybenkov V V, Shaw S Y, Sokal A D, Sumners D W, Szafron M L, Szafron M L, Trigueros S, Vologodskii A, Yan J   +38 more
core   +1 more source