Results 121 to 130 of about 1,241,674 (300)
, 2007 The story of American democracy is often told as the steady expansion of voting but history has not yet caught up with one group -- former felons. In the early American political system, the right to vote was reserved for white males over the age of 21 ...
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Molecular Oncology, EarlyView.Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen +14 more
wiley +1 more source
Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
Molecular Oncology, EarlyView.IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source
Molecular Oncology, EarlyView.We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober +16 more
wiley +1 more source
Financial modernization : a new world or status quo? [PDF]
The passage of the Gramm-Leach-Bliley Act (GLB) in 1999 was a milestone in financial services regulation. GLB repealed restrictions dating back to the Depression against the commingling of securities, insurance and other financial service activities ...
Joe Van Walleghem
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Expanding Resources for Service: Strategies from State Commissions [PDF]
, 1997 In response to the passage of the National and Community Service Trust Act in 1993, state-level Commissions were created to direct federal funds to local service programs, monitor program progress and quality, and to determine the content and direction ...
Kathryn Furano, Linda Z. Jucovy
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Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae
FEBS Open Bio, EarlyView.Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj +3 more
wiley +1 more source
Determinants of Labor Market Outcomes of Disabled Men Before and After the Americans with Disabilities Act of 1990 [PDF]
The study compares the labor market experience of men with disabilities before and after the Americans with Disabilities Act of 1990. The handful of studies that have focused on the wage impact of disabilities have either not fully incorporated the ...
Choe, Chung
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A faded passion? Estes Kefauver and the senate subcommittee on antitrust and monopoly [PDF]
, 2007 In this paper I examine the U.S. Senate subcommittee on antitrust and monopoly (1957-1963), chaired by Tennessee Senator Estes Kefauver. I assess the persistence into the postwar years of the antimonopoly critique of bigness that had animated the ...
Scroop, D.
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FEBS Open Bio, EarlyView.CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point +7 more
wiley +1 more source