Results 71 to 80 of about 10,245,750 (302)

Dynamic Characteristic and Parameter Analysis of a Modular Building with Suspended Floors

Buildings, 2022
Over the past few years, modular buildings have become an important form of environmentally friendly architecture. Prefabricated construction methods have gained a lot of attention because they produce less construction waste and require less labor and ...
Qingguang He, Shiquan Zhang, Jiying Shang   +2 more
doaj   +1 more source

Passivity-Based Control [PDF]

, 2019
Stabilization of physical systems by shaping their energy function is a well-established technique whose roots date back to the work of Lagrange and Legendre. Potential energy shaping for fully actuated mechanical systems was first introduced in Takegaki and Arimoto (Trans ASME J Dyn Syst Meas Control 12:119--125, 1981) more than 30 years ago.
Ortega, Romeo, Borja, Pablo
openaire   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

Molecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary, Jose Javier Bravo‐Cordero   +1 more
wiley   +1 more source

FPGA-based gait control system for passive bipedal robot

, 2007
In this paper, we present a Field Programmable Gate Array (FPGA) based high-performance gait control system for passive bipedal robots with complex mechanical structures and multiple degrees of freedoms in body and limbs. The system utilizes the hardware
Wang, Long, Qining, Wang, Long Wang, Jingeng, Mai, Jingeng Mai, Mai, Jingeng, Qining Wang, Long, Wang, Wang, Qining   +8 more
core   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

Sampled Data Systems Passivity and Discrete Port-Hamiltonian Systems [PDF]

, 2005
In this paper, we present a novel way to approach the interconnection of a continuous and a discrete time physical system. This is done in a way which preserves passivity of the coupled system independently of the sampling time T.
van der Schaft, Arjan, S. Stramigioli, Schaft, Arjan J. van der,, Schaft, Arjan J. van der; id_orcid, Secchi, Cristian,, Fantuzzi, Cesare,, Stramigioli, Stefano; id_orcid, SECCHI, Cristian, Stramigioli, Stefano,, AJ Van der Schaft, Schaft, Arjan J. van der, FANTUZZI, Cesare, Stramigioli, Stefano   +12 more
core   +3 more sources

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

Molecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim, Hwiyeong Lee, Jin Hong, Daechan Park   +3 more
wiley   +1 more source

Translating whole‐genome doubling into precision medicine in cancer

Molecular Oncology, EarlyView.
Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley   +1 more source

The innovative energy-absorbing damper hybrid of steel and GFRP rods [PDF]

Numerical Methods in Civil Engineering
In the present study, a novel hybrid damper is introduced based on the combination of steel and glass-fibers reinforced-polymer (GFRP) rods. Sharing effort of the appropriate energy absorption properties of steel subjected to hysteretic loads and the ...
amir farrokhi, seyed bahram beheshti
doaj   +1 more source

PANoptosis in the pathogenesis of myelodysplastic syndromes

Molecular Oncology, EarlyView.
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla, Jyoti Lamichhane, Cameron Lewis, Peter Breslin, Jiwang Zhang   +4 more
wiley   +1 more source