Results 61 to 70 of about 433,714 (266)

The innovative energy-absorbing damper hybrid of steel and GFRP rods [PDF]

open access: yesNumerical Methods in Civil Engineering
In the present study, a novel hybrid damper is introduced based on the combination of steel and glass-fibers reinforced-polymer (GFRP) rods. Sharing effort of the appropriate energy absorption properties of steel subjected to hysteretic loads and the ...
amir farrokhi, seyed bahram beheshti
doaj   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

open access: yesFEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová   +2 more
wiley   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

open access: yesFEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova   +2 more
wiley   +1 more source

Dose‐dependent hepatotoxicity of hydrogen peroxide in HepG2 cells and its modulation by CYP450 induction

open access: yesFEBS Open Bio, EarlyView.
NMR metabolomics revealed concentration‐dependent metabolic perturbations in HepG2 cells exposed to H2O2. Rifampicin pretreatment enhanced metabolic competence, attenuated toxin‐induced alterations and produced metabolite profiles more consistent with human liver physiology, supporting the use of CYP450‐induced HepG2 models for improved in vitro ...
Maren Jinks   +4 more
wiley   +1 more source

AN ANALYSIS OF A PIEZO-ELASTIC RESTRICTOR USING A CAPACITIVE SHUNT

open access: yesTASK Quarterly, 2004
The study investigates the control of structural response using collocated piezoelectric elements mounted on both sides of beam. A capacitive shunt is introduced into the circuitry to provide passive control of the beam’s configuration.
MARINO KEKANA, JANUSZ BADUR
doaj  

Passive Control Measures of Wind Flow around Tall Buildings

open access: yesBuildings
The growth and diversification of tall buildings demands higher performance standards that encompass serviceability and resilience. In this respect, the control of air flow around tall buildings poses challenges to minimising the energy that could induce
Mario A. Aguirre-López   +2 more
doaj   +1 more source

Aging Is a Key Driver for Adult Acute Myeloid Leukemia

open access: yesAging and Cancer, EarlyView.
Acute myeloid leukemia (AML) is a classical age‐related hematologic malignancy, and a key driver of AML is aging, which profoundly regulates intrinsic factors such as genomic instability, epigenetic reprogramming, and metabolic dysregulation, and alters bone marrow microenvironment.
Rong Yin, Haojian Zhang
wiley   +1 more source

Efficacy of Intermittent Theta‐Burst Stimulation for Prolonged Disorders of Consciousness: A Prospective, Randomized, Controlled Trial

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Emerging evidence suggests that low‐frequency neural oscillations are dynamically regulated by consciousness levels, with the recovery of low cortical activity potentially serving as a neurophysiological substrate for conscious emergence. Targeted enhancement of these low‐frequency rhythms in patients with disorders of consciousness
Chuan Xu   +10 more
wiley   +1 more source

Comparative Analysis of Seismic–Induced Vibration Response Control in Multi–Inerter–Negative Stiffness Damped Outrigger Systems

open access: yesBuildings
The functionality and structural safety of super high–rise buildings are significantly challenged during seismic events. Although conventional damped outrigger (CDO) systems effectively mitigate seismic–induced vibrations, the energy dissipation capacity
Shuaiqiang Wei   +3 more
doaj   +1 more source

Normal‐Appearing White Matter Injury Mediates Chronic Deep Venous Hypoxia and Disease Progression in Multiple Sclerosis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To explore how cerebral hypoxia and Normal‐Appearing White Matter (NAWM) integrity affect MS lesion burden and clinical course. Methods Seventy‐nine MS patients, including 13 clinically isolated syndrome (CIS) patients and 66 relapsing–remitting multiple sclerosis (RRMS) patients, and 44 healthy controls (HCs) were recruited from ...
Xinli Wang   +8 more
wiley   +1 more source

Home - About - Disclaimer - Privacy