Results 131 to 140 of about 38,122 (295)
Heart dysfunction in a rat model with autosomal recessive polycystic kidney disease
Abstract figure legend Our results demonstrate a diastolic dysfunction in animals with severe kidney disease. Moreover, chronic kidney disease (CKD)‐induced heart fibrosis and hypertrophy are associated with a dysregulation of cardiokine signalling in autosomal recessive polycystic kidney disease (ARPKD) animals. Created using BioRender.com.
Nathalie Gayrard+11 more
wiley +1 more source
How not to talk about passive euthanasia: A lesson from India [PDF]
Iain Brassington
openalex +1 more source
Attitudes of Registered Nurses in Designated South Dakota Hospitals Toward Aspects of Terminal Patient Care and Euthanasia [PDF]
The problem under investigation in this study is: What are the attitudes of professional nurses in designated hospitals in South Dakota toward the practice of passive and active euthanasia, and how do these attitudes vary when controlled for selected ...
Hofland, Sharon Ann
core +1 more source
MTCH2 Suppresses Thermogenesis by Regulating Autophagy in Adipose Tissue
This study demonstrates that MTCH2 acts as an evolutionarily conserved regulator of energy homeostasis across Drosophila, rodents, and humans. Adipose‐specific MTCH2 ablation enhances brown/beige adipose thermogenesis through Bcl‐2‐dependent autophagy, promoting energy expenditure and counteracting obesity‐associated metabolic disorders. These findings
Xin‐Yuan Zhao+17 more
wiley +1 more source
Are Passive Spiral Galaxies truly 'passive' and 'spiral'?: a Near-Infrared perspective [PDF]
Passive spiral galaxies - unusual galaxies with spiral morphologies but without any sign of on-going star formation - have recently been shown to exist preferentially in cluster infalling regions. This discovery directly connects passive spiral galaxies to cluster galaxy evolution studies, such as the Butcher-Oemler effect or the morphology-density ...
arxiv
Abstract INTRODUCTION Deficiency in the aquaporin‐4 (AQP4) water channel has been linked to impaired amyloid beta (Aβ) clearance. However, a detailed morphopathological analysis of amyloid deposition following AQP4 therapeutic modulation remains unexplored.
Marina Daniela Manescu+10 more
wiley +1 more source
Controversies Surrounding the Hopelessly Ill Patient [PDF]
Dr. Cassem, who acted as Guest Editor for this issue of the Linacre Quarterly, is Associate Professor of Psychiatry, Harvard Medical School, and is a member of the psychiatry staff at Massachusetts General Hospital.
Cassem, Ned H.
core +1 more source
Role of STING Deficiency in Amelioration of Mouse Models of Lupus and Atherosclerosis
Objective Systemic lupus erythematosus (SLE) is a systemic autoimmune syndrome characterized by autoreactive responses to nucleic acids, dysregulation of the type I interferon (IFN‐I) pathway, and accelerated atherosclerosis. The stimulator of IFN genes (STING), a cytosolic DNA sensor, has pathogenic implications in various inflammatory diseases ...
Yudong Liu+10 more
wiley +1 more source
In response to enzymatic activity within the tumor microenvironment, remotely actuated microrobots designed for localized delivery of stimuli‐responsive hydrogels engineered to release chemotherapeutics (ChemoBots) are developed. The system leverages magnetic navigation for targeted localization and prolongsed drug release, achieving marked tumor ...
Mingzhen Tian+4 more
wiley +1 more source
New experimental model of exposure to environmental tobacco smoke [PDF]
PURPOSE: To describe a new model to passive smoking for rodents. METHODS: Twenty rats were distributed into two study groups (N=10): control group (CG), that was not exposed to tobacco smoke and used as normal standard for biochemical and histological ...
Marcus Vinicius Henriques Brito+6 more
doaj