Poor aqueous solubility limits the anticancer application of tricin (TRI). TRI‐loaded liposomes (TRI@Lips) with favorable physicochemical properties are constructed. The nanoplatform improves cellular uptake, exhibits potent in vitro anti‐gastric‐cancer activity, and accumulates in tumor sites via the EPR effect to achieve dose‐dependent in vivo tumor ...
Baiji Cui +5 more
wiley +1 more source
Definitional confusion in nurses' and physicians' attitudes toward euthanasia in India: A systematic review and meta-analysis. [PDF]
Kashyap K, Gielen J.
europepmc +1 more source
Single‐nucleus sequencing identified a semaphorin 3C (SEMA3C)‐high stem‐like tumour subpopulation that drives gastric cancer peritoneal metastasis through early B‐cell factor 2 (EBF2)‐mediated FGF7 expression and enhanced FGF7–FGFR2 signalling with endothelial cells. Targeting the FGF–FGFR pathway may provide a promising therapeutic strategy.
Yajing Zhou +12 more
wiley +1 more source
Passive and active euthanasia : is there any moral difference?
tag=1 data=Passive and active euthanasia : is there any moral difference? tag=2 data=Mettyear, Bill tag=3 data=Modern Medicine of Australia tag=6 data=^d ^mOCT ^y1991 tag=8 data=DEATH tag=10 data=IN QLD.PARLIAMENTARY LIBRARY.INFORMATION KIT NO.45
Mettyear, Bill
core
ABSTRACT Spinal cord injury (SCI) poses a formidable challenge in regenerative medicine, with current therapeutic strategies proving largely unsuccessful in achieving functional repair. Notably, paediatric patients and neonatal mice exhibit spontaneous and efficient regeneration after SCI, while the mechanisms remain elusive.
Yongfeng Zhang +31 more
wiley +1 more source
ABSTRACT Cartilage is traditionally viewed as a metabolically quiescent tissue that relies primarily on exogenous lipid uptake to meet its energetic and structural demands. However, increasing evidence suggests that chondrocytes exhibit metabolically active behaviors, particularly under aging and pathological conditions.
Shadi Moradi, Anupama Binoy, Shouan Zhu
wiley +1 more source
Correction: Comparison of attitudes towards five end-of-life care interventions (active pain control, withdrawal of futile life-sustaining treatment, passive euthanasia, active euthanasia and physician-assisted suicide): a multicentred cross-sectional survey of Korean patients with cancer, their family caregivers, physicians and the general Korean population. [PDF]
europepmc +1 more source
Letter: Active and passive euthanasia. [PDF]
A G, Flew, R G, Twycross
openaire +2 more sources
Failed Mucosal Allostasis Distinguishes Murine IgG‐ From IgE‐Mediated Recurrent Severe Anaphylaxis
This study investigates IgE‐ and IgG‐mediated pathways in acute and recurrent anaphylaxis using a murine ASA‐PSA model, assessing barrier integrity, immune activation and tissue remodelling across pulmonary and intestinal compartments. Recurrent IgE‐ and IgG‐mediated anaphylaxis produces divergent mucosal outcomes despite comparable systemic severity ...
Abdurrahman Simsek +8 more
wiley +1 more source
Patient autonomy versus family centric decision making in end-of-life care. [PDF]
Shahid R, Irfan M, Shah SSH.
europepmc +1 more source

