Results 131 to 140 of about 628,667 (249)

Adaptation of Echinococcus Multilocularis to Oxidative Stress Depends on EmPDK‐Mediated Metabolic Reprogramming

Advanced Science, Volume 13, Issue 59, 23 October 2026.
Metabolic adaption presents a vital survival strategy for E. multilocularis. This study identifies EmPDK as a central metabolic regulator governing glucose metabolic reprogramming. Oxidative stress activates EmHIF1α to induce EmPDK expression. Mechanistic characterization reveals this ROS/EmHIF1α/EmPDK axis drives glycolytic reprogramming to sustain ...
Huijuan Wang, Zhijian Xu, Ye Tian, Yao Zhang, Zhe Cheng, Yanhai Wang   +5 more
wiley   +1 more source

THE RIGHT TO LIFE AND EUTHANASIA

Pravo, 2015
THIS study shows legal inconsistencies, dilemmas and insufficiently precise defined terms which make the fundamental human right – right to life. Some problems of this sacred human right were reviewed such as a legalization of abortion and dilemma ...
Mirjana Živković
doaj  

Euthanasia : its Definition, Classification, and Ethical Justification

, 2000
Nowadays, the most important question arising in the medical situation is not whether euthanasia is ethically acceptable, but what are the acceptable guidelines for euthanasia.
손명세
core  

Systematic Multi‐Level Analyses Decode the Arthritis‐Neurodegeneration Axis With In Vivo Validation

Advanced Science, Volume 13, Issue 60, 28 October 2026.
Arthritis and neurodegeneration are usually studied as separate disorders, but this study connects them through population evidence, genetic inference, transcriptomic mapping, and mouse models. It highlights RNF40 as a context‐dependent joint‐brain candidate, induced in inflammatory joints yet functionally linked to dopamine‐neuron vulnerability ...
Jinwen Wang, Wenhui Xie, Lei Yang, Zhengrong Wang, Yi Huang, Peng Huang, Yuan Liu, Jun Hu   +7 more
wiley   +1 more source

Sonoselective Transfection of Glioma Endothelium

Advanced Science, Volume 13, Issue 60, 28 October 2026.
Delivering non‐viral, gene‐bearing nanoparticles with thiol‐decorated surfaces to gliomas with focused ultrasound yields transfection tropism for endothelial cells. From this platform, “sonoselective” transfection of glioma endothelium is achieved via incorporation of an endothelial cell‐specific promoter.
Anna C. Debski, Catherine M. Gorick, Victoria R. Breza, Jackson Tirrell, Krishan Perumal, Katherine M. Nowak, Ji Song, Natasha D. Sheybani, Richard J. Price   +8 more
wiley   +1 more source

The nurse and euthanasia

, 1980
The study was designed to compare and contrast responses of two groups of nurses to situational case studies relative to death and dying, with particular emphasis on euthanasia.
Babcock, Patricia Ann
core  

Chimeric IL‐6/4R‐LL37 Engineered Macrophages Achieve Synchronized Inflammation Control and Antimicrobial Defence in Sepsis

Advanced Science, Volume 13, Issue 60, 28 October 2026.
Engineered macrophages programmed in situ by LNP‐delivered IL‐6/4 fusion and LL37 mRNAs simultaneously dampen cytokine storm, promote M2‐like repair, and enhance direct bacterial killing in sepsis. This combinatorial strategy restores T cell and macrophage function, lowers organ bacterial burden, and improves survival, highlighting a precision, host ...
Tianyang Jie, Zheyu Zhang, Hao Zhang, Linke Bian, Penglong Zheng, Sijia Zhou, Minqi Wang, Mingyu Qu, Yufei Wang, Xinhua Qu, Bing Yue   +10 more
wiley   +1 more source

Quando a morte é um ato de cuidado: obstinação terapêutica em crianças

Cadernos de Saúde Pública
Este artigo discute um caso específico de recusa de obstinação terapêutica para um bebê de oito meses, portador de Amiotrofia Espinhal Progressiva Tipo I, uma doença genética incurável, degenerativa e com curto prognóstico médico de sobrevida.
Debora Diniz
doaj  

Biological Insights Into Filopaludina bengalensis (Lamarck, 1822): An Ecologically and Economically Edible Freshwater Snail of South Asia

Aquaculture, Fish and Fisheries, Volume 6, Issue 5, October 2026.
ABSTRACT Freshwater snails play important ecological and socio‐economic roles across South Asia, yet basic biological information on Filopaludina bengalensis (Lamarck, 1822) (Gastropoda: Viviparidae) remains scarce. Growth performance, reproductive biology and embryonic development of F.
Alif Layla Bablee, Abu Ayub Ansary, Md. Naim Mahmud, Mashruka Jeba, Louise von Gersdorff Jørgensen, Md. Mehedi Alam, Neaz A. Hasan, Niels O. G. Jørgensen, Lars Hestbjerg Hansen, Mohammad Mahfujul Haque   +9 more
wiley   +1 more source

Knowledge, attitude, and acceptance of euthanasia among medical students and doctors in Pakistan: A cross-sectional study. [PDF]

Medicine (Baltimore)
Raza A, Sajjad W, Rehman UU, Farooqi H, Khan Z, Imtiaz A, Ullah Khan F, Azeem D, Abdel-Akher A, Aleem A, Mufti F, Nawaz S, Nayyar A, Jamshed A, Farrukh A, Zahir M, Qamar I.   +16 more
europepmc   +1 more source