Results 51 to 60 of about 171,945 (297)

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

FEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli, Mohammad Nour Alsamsam, Ugnė Bagdonaitė, Van Truc Vu, Chun‐Jen Huang, Polina Kuzhir, Mindaugas Zaremba, Aurimas Kopūstas, Marijonas Tutkus   +8 more
wiley   +1 more source

Experimental and Computational Investigation of an “Open” Transonic Cavity Flow [PDF]

, 2009
This paper presents an investigation of a transonic flow (M∞ = 0.85) over a rectangular cavity having a length-to-depth ratio of 5. Velocities were measured inside the cavity on the central plane and two off-centre planes using a two-component particle ...
Knowles, Kevin, Atvars, K., Ritchie, S. A., Lawson, Nicholas J.   +3 more
core   +1 more source

Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface

FEBS Open Bio, EarlyView.
HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana, Avigail Yariv, Tal Oppenheim, Hadar Amartely, Dana Reichmann, Oded Livnah   +5 more
wiley   +1 more source

Vortex suppression of the tip leakage flow over a NACA0009 hydrofoil via a passive jet induced by the double-control-hole [PDF]

, 2021
Tip leakage vortex (TLV) frequently occurring in bladed energy conversion machines may induce flow loss as well as cavitation. The double-curved-hole (DC hole) structures located at the 10%–25% chord near the leading edge of the foil are adopted to ...
Zhang, Guangjian, van Esch, Bart P.M., Wang, Fei, Huang, Yadong, Zhang, Desheng, van Esch, Bart P.M.; id_orcid   +5 more
core   +1 more source

Passive Control Measures of Wind Flow around Tall Buildings

Buildings
The growth and diversification of tall buildings demands higher performance standards that encompass serviceability and resilience. In this respect, the control of air flow around tall buildings poses challenges to minimising the energy that could induce
Mario A. Aguirre-López, Filiberto Hueyotl-Zahuantitla, Pedro Martínez-Vázquez   +2 more
doaj   +1 more source

Dose‐dependent hepatotoxicity of hydrogen peroxide in HepG2 cells and its modulation by CYP450 induction

FEBS Open Bio, EarlyView.
NMR metabolomics revealed concentration‐dependent metabolic perturbations in HepG2 cells exposed to H2O2. Rifampicin pretreatment enhanced metabolic competence, attenuated toxin‐induced alterations and produced metabolite profiles more consistent with human liver physiology, supporting the use of CYP450‐induced HepG2 models for improved in vitro ...
Maren Jinks, Garth L. Maker, Emily C. Davies, Berin A. Boughton, Samantha Lodge   +4 more
wiley   +1 more source

Passive Sliding Mode Controlled UPFC and its Treatment Strategy of Unbalanced Grid Conditions

Frontiers in Energy Research, 2021
Modular multilevel converter based unified power flow controller (MMC-UPFC) can provide flexible power regulation and plays an important role in the smart grid and future distribution networks.
Yang Chen, Han Wang, Miao Zhu, Ming Liu, Jianjun Ma, Xu Cai   +5 more
doaj   +1 more source

Passive control of circular cylinder wake in shallow flow

Measurement, 2013
Abstract The control of vortex shedding of a circular cylinder in shallow water using a splitter plate located in the downstream of the circular cylinder was studied by employing particle image velocimetry (PIV) technique. Experiments were carried out in a water channel having a test section of 8000 mm × 1000 mm × 750 mm dimensions at a Reynolds ...
Gozmen, Bengi, Akilli, Huseyin, Sahin, Besir   +2 more
openaire   +2 more sources

Efficacy of Intermittent Theta‐Burst Stimulation for Prolonged Disorders of Consciousness: A Prospective, Randomized, Controlled Trial

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Emerging evidence suggests that low‐frequency neural oscillations are dynamically regulated by consciousness levels, with the recovery of low cortical activity potentially serving as a neurophysiological substrate for conscious emergence. Targeted enhancement of these low‐frequency rhythms in patients with disorders of consciousness
Chuan Xu, Jun Hu, Qianqian Wu, Min Wu, Yamei Yu, Hangcheng Li, Jian Gao, Jingqi Li, Nai Ding, Jie Yu, Benyan Luo   +10 more
wiley   +1 more source

Normal‐Appearing White Matter Injury Mediates Chronic Deep Venous Hypoxia and Disease Progression in Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To explore how cerebral hypoxia and Normal‐Appearing White Matter (NAWM) integrity affect MS lesion burden and clinical course. Methods Seventy‐nine MS patients, including 13 clinically isolated syndrome (CIS) patients and 66 relapsing–remitting multiple sclerosis (RRMS) patients, and 44 healthy controls (HCs) were recruited from ...
Xinli Wang, Huiying Wang, Zhizheng Zhuo, Ai Guo, Ke Lv, Decai Tian, Chao Chai, Yunyun Duan, Shuang Xia   +8 more
wiley   +1 more source