Results 31 to 40 of about 75,448 (244)

DIAGNÓSTICO DE FALHA DE TRANSFERÊNCIA DE IMUNIDADE PASSIVA EM BEZERROS ATRAVÉS DA DETERMINAÇÃO DE PROTEÍNA TOTAL E DE SUAS FRAÇÕES ELETROFORÉTICAS, IMUNOGLOBULINAS G E M E DA ATIVADE DA GAMA GLUTAMIL TRANSFERASE NO SORO SANGÜÍNEO DIAGNOSIS OF PASSIVE IMMUNITY TRANSFER FAILURE IN CALVES BY TOTAL PROTEIN AND ITS ELETROPHORETIC FRACTIONS, IMMUNOGLOBULINS G AND M QUANTIFICATION AND GAMMA GLUTAMYL TRANFERASE ACTIVITY IN SERUM

open access: yesCiência Rural, 2001
Determinou-se a concentração de proteína total e de suas frações (albumina, alfa globulina, beta globulina e gama globulina), imunoglobulinas G e M, bem como, a atividade da gama glutamil transferase (GGT) em amostras sangüíneas de 40 bezerros com 24 ...
Francisco Leydson Formiga Feitosa   +3 more
doaj   +1 more source

Human Milk Antibodies after BNT162b2 Vaccination Exhibit Reduced Binding against SARS-CoV-2 Variants of Concern

open access: yesVaccines, 2022
SARS-CoV-2-specific antibody responses are engendered in human milk after BNT162b2 vaccination. However, the emergence of variants of concern (VOCs) raises concerns about the specificity of and potential cross-protection mediated by milk antibody ...
Jia Ming Low   +6 more
doaj   +1 more source

Preventing invasive meningococcal disease in early infancy

open access: yesHuman Vaccines & Immunotherapeutics, 2022
This review considers the pathogenesis, diagnosis, and epidemiology of invasive meningococcal disease in infants, to examine and critique meningococcal disease prevention in this population through vaccination.
Jessica Presa   +3 more
doaj   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

open access: yesMolecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos   +6 more
wiley   +1 more source

A Potential of an Anti-HTLV-I gp46 Neutralizing Monoclonal Antibody (LAT-27) for Passive Immunization against Both Horizontal and Mother-to-Child Vertical Infection with Human T Cell Leukemia Virus Type-I

open access: yesViruses, 2016
Although the number of human T-cell leukemia virus type-I (HTLV-I)-infected individuals in the world has been estimated at over 10 million, no prophylaxis vaccines against HTLV-I infection are available.
Hideki Fujii   +6 more
doaj   +1 more source

Comprehensive serologic profile and specificity of maternal and neonatal cord blood SARS-CoV-2 antibodiesAJOG Global Reports at a Glance

open access: yesAJOG Global Reports, 2022
BACKGROUND: Initial studies on COVID-19 in pregnancy have demonstrated a range of neutralizing activity, but little has been published on the full profile of SARS CoV-2 related antibodies in maternal and cordblood. OBJECTIVE: This study aimed to describe
Rupsa C. Boelig, MDMS   +6 more
doaj   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

open access: yesMolecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary   +1 more
wiley   +1 more source

Evaluation of passive immunity from dams previously immunized with an inactivated glycoprotein E-deleted infectious bovine rhinotracheitis marker vaccine after challenge infection with wild-type bovine alphaherpesvirus 1 in calves

open access: yesVaccine: X
Bovine alphaherpesvirus 1 (BoAHV-1) is a major cattle pathogen that causes infectious bovine rhinotracheitis (IBR) and other respiratory and reproductive disorders, resulting in substantial global economic losses to the cattle industry.
Stefano Petrini   +13 more
doaj   +1 more source

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