Results 41 to 50 of about 982,375 (281)

Radiation-attenuated schistosome vaccination--a brief historical perspective. [PDF]

, 2009
The high level of protection which can be induced by vaccination of a range of hosts, from rodents to primates, with live radiation-attenuated schistosome larvae offers great promise for development of a human schistosome vaccine.
Bickle, QD, Q. D. BICKLE
core   +1 more source

Decoding the dynamic extracellular matrix in cancer—3D models and bioscaffolds rewire the rules of tumor progression

FEBS Letters, EarlyView.
Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani, Konstantinos Spanopoulos, Zoi Piperigkou, Nikos K. Karamanos   +3 more
wiley   +1 more source

Preventing invasive meningococcal disease in early infancy

Human Vaccines & Immunotherapeutics, 2022
This review considers the pathogenesis, diagnosis, and epidemiology of invasive meningococcal disease in infants, to examine and critique meningococcal disease prevention in this population through vaccination.
Jessica Presa, Lidia Serra, Catherine Weil-Olivier, Laura York   +3 more
doaj   +1 more source

Epigenetic reprogramming of lineage switching in cancer

FEBS Letters, EarlyView.
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı, Burcu Akman, Ezgi Bağırsakçı, Nese Atabey, Serap Erkek‐Ozhan   +4 more
wiley   +1 more source

Membrane composition and thermodynamic identity as boundaries of life for synthetic cell research

FEBS Letters, EarlyView.
What makes a cell a cell? The boundary of a living cell is not just a wall. Read as a Markov blanket, the membrane separates internal from external states, generating identity and non‐equilibrium order. Can this identity be rebuilt from scratch in a synthetic cell?
Caterina Presutti, Bert Poolman
wiley   +1 more source

A Potential of an Anti-HTLV-I gp46 Neutralizing Monoclonal Antibody (LAT-27) for Passive Immunization against Both Horizontal and Mother-to-Child Vertical Infection with Human T Cell Leukemia Virus Type-I

Viruses, 2016
Although the number of human T-cell leukemia virus type-I (HTLV-I)-infected individuals in the world has been estimated at over 10 million, no prophylaxis vaccines against HTLV-I infection are available.
Hideki Fujii, Mamoru Shimizu, Takuya Miyagi, Marie Kunihiro, Reiko Tanaka, Yoshiaki Takahashi, Yuetsu Tanaka   +6 more
doaj   +1 more source

Geothermal ground heat exchangers in Malta : thermal performance assessment of infill grouts [PDF]

, 2013
The aim of this paper was to assess the thermal conductivity of proprietary grout mixes versus local ones in Malta. Ground source heat pump (GSHP) systems consume 75% less electricity than conventional environmental control systems and have lower ...
Runco, Lara, PLEA2013 - 29th Conference, Sustainable Architecture for a Renewable Future, Passive & Low Energy Architecture (PLEA), Buhagiar, Vincent   +3 more
core  

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Evaluation of passive immunity from dams previously immunized with an inactivated glycoprotein E-deleted infectious bovine rhinotracheitis marker vaccine after challenge infection with wild-type bovine alphaherpesvirus 1 in calves

Vaccine: X
Bovine alphaherpesvirus 1 (BoAHV-1) is a major cattle pathogen that causes infectious bovine rhinotracheitis (IBR) and other respiratory and reproductive disorders, resulting in substantial global economic losses to the cattle industry.
Stefano Petrini, Alessandra Martucciello, Cecilia Righi, Giovanna Cappelli, Giulia Costantino, Carlo Grassi, Cristina Casciari, Eleonora Scoccia, Elena Tinelli, Giorgio Galiero, Monica Giammarioli, Esterina De Carlo, Roberto Sabato, Francesco Feliziani   +13 more
doaj   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

Molecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary, Jose Javier Bravo‐Cordero   +1 more
wiley   +1 more source